Absstract of: US2025079008A1
Disclosed herein are system, method, and computer program product embodiments for improving detection and treatment of patient conditions based on continuous analyte data. The disclosed techniques utilize analyte data, such as lactate, glucose, and creatinine, provided from a continuous analyte sensor to predict patient outcomes. The prediction may also take into account other medical information associated with the patient, such as patient vital signs and medical history. The disclosed system allows for early and non-invasive prediction of patient outcomes in various settings including a hospital setting, a home setting, disease (e.g., heart failure, sepsis) detection, and high risk surgery monitoring. The disclosed system also is configured to monitor patient conditions and generating alerts and/or notifications based on the predicted patient outcomes to provide preemptive treatment of patient conditions.
Absstract of: US2025073386A1
A device for delivering insulin to a user, the device configured as a wearable apparatus or system in which continuous glucose monitoring (CGM), insulin delivery and control functionality are provided to ensure insulin is delivered to the user, the device comprising: a reservoir for storing insulin; a catheter configured to deliver insulin to a subcutaneous layer of the user; an introducer needle movable with respect to the catheter, the introducer needle configured to facilitate (a) insertion of the catheter into the subcutaneous layer of the user and (b) removal of the introducer needle to enable delivery of insulin through the catheter; a micropump, in fluid communication with the reservoir and catheter, for pumping insulin from the reservoir through the catheter; and a pressure sensor separate from and in fluid communication with an outlet port of the micropump, the sensor comprising: a first wafer defining an inlet port, and outlet port and fluid channel communicating with the inlet and outlet ports; a second wafer covering the fluid channel and including a pressure sensing mechanism; and a piezoelectric device layered on the first wafer and configured to generate a signal in response to the pressure sensing mechanism that is representative of pressure within channel.
Absstract of: WO2023211879A1
Disclosed herein are apparatuses and methods that can simplify delivery of meal boluses in diabetes therapy. Rather than requiring a user to enter a number of carbohydrates for a given meal, the system can automatically provide a predetermined amount of insulin when the user indicates that a meal is going to be consumed. Providing such predetermined, fixed meal boluses provides a lower cognitive burden alternative for the mealtime experience.
Absstract of: WO2023212738A1
Disclosed is a meal detection and meal size estimation machine learning technology. In some embodiments, the techniques entail applying to a trained multioutput neural network model a set of input features, the set of input features representing glucoregulatory management data, insulin on board, and time of day, the trained multioutput neural network model representing multiple fully connected layers and an output layer formed from first and second branches, the first branch providing a meal detection output and the second branch providing a carbohydrate estimation output; receiving from the meal detection output a meal detection indication; and receiving from the carbohydrate estimation output a meal size estimation.
Absstract of: ES3000778A2
A botulinum toxin syringe having a barrel has volumetric marking graduations scaled at four units per 0.1 mL. These volumetric marking graduations allow for ease of unit conversion and can reduce the likelihood of overdosing or under dosing of botulinum toxin. The syringe may further comprise further volumetric marking graduations configured to be interchangeably used for administration of insulin or botulinum toxin. The syringe may further comprise further volumetric marking graduations configured for interchangeably use for administration of different types of botulinum toxin.
Absstract of: WO2025041079A1
The present invention relates to an automatic diabetic foot scanner (1), comprising of, a housing (2), a control unit (3), a communication module (4). The housing (2) accommodates a plurality of modules for detecting a diabetic foot and said plurality of modules are operated by a single on-chip board (18). The plurality of modules include a neuropathy assessment module (5), a blood circulation assessment module (6) and a plantar pressure measurement module (7). Further, the present invention is a cost friendly and portable solution of detecting diabetic foot.
Absstract of: US2025070458A1
A glucose monitoring device is provided. The glucose monitoring device includes a housing having a first portion and a second portion, the second portion operable to be placed adjacent to a human body during operation of the glucose monitoring device. The glucose monitoring device further includes a circuit board positioned between the first portion and the second portion of the housing, the circuit board having a trace antenna. The glucose monitoring device further includes a conductive structure spaced apart from the circuit board.
Absstract of: US2025064359A1
Disclosed are devices, systems and methods for in vivo monitoring of localized environment conditions within a patient user by measuring analytes, including glucose, oxygen, and/or other analytes. In some aspects, a sensor device includes a wafer-based substrate, at least one electrochemical sensor two-electrode contingent including a working electrode and a reference electrode on the substrate and configured to detect a target analyte in a body fluid when the sensor device is deployed within a subject's body, where the working electrode is functionalized by a chemical layer configured to facilitate a reaction involving the target analyte that produces an electrical signal; and an electronics unit in communication with the electrochemical sensor electrode contingent to transmit the electrical signal to an external processor.
Absstract of: US2025064361A1
An analyte sensor for use in medical devices for measuring analyte data in an analyte carrying fluid, in particular for measuring glucose data, which includes: a first electrode being a working electrode, a second electrode, a substrate carrying the first electrode and the second electrode, at least one membrane which at least partially covers the first electrode, wherein the at least one membrane comprises a membrane material that is impermeable to the analyte carrying fluid and/or the analyte, wherein the at least one membrane comprises at least one opening, and wherein the at least one membrane is configured for controlling the flux of the analyte carrying fluid and/or the analyte to the first electrode via the at least one opening. Methods of operation, a continuous analyte monitoring system and a kit with such a sensor are also disclosed.
Absstract of: US2025064350A1
A continuous glucose monitor, comprising a housing and a circuit board arranged in the housing, wherein an electronic component is carried on the circuit board; a probe assembly configured to penetrate skin and connected to the circuit board; and an auxiliary sensor connected to the circuit board and configured to detect a compressed state of the continuous glucose monitor. The continuous glucose monitor provided in the present disclosure can identify its own compressed state, thereby improving the accuracy of glucose measurement.
Absstract of: US2025064362A1
An embodiment may provide a method for calibrating sensitivity for glucose measurement including: obtaining an offset value for determining sensitivity; determining a first sensitivity from a sensor data and a reference glucose value, based on the offset value; and determining sensitivity by adjusting the first sensitivity, wherein the determining of the sensitivity includes obtaining one sensitivity, and determining sensitivity A by adjusting the one sensitivity by reflecting an average sensor data obtained by averaging a plurality of sensor data and an average glucose value obtained by averaging a plurality of glucose values to the one sensitivity; and determining the sensitivity A as the sensitivity.
Absstract of: US2025064327A1
The present invention discloses a biosensor system designed for non-invasive measurement and prediction of blood glucose and blood pressure levels. The system comprises a biosensor module, a processing module, a convolutional neural network (CNN) module, a display module, a user interface module, and a control module. The biosensor module incorporates optical spectroscopic techniques to capture physiological signals, which are preprocessed to eliminate noise and optimize for subsequent analysis. A scalogram image is generated from the preprocessed signals, and the processing module further processes the image. The CNN module utilizes the processed scalogram image to accurately measure and predict blood glucose and blood pressure levels. The system offers a user-friendly interface displayed on a screen, enabling users to interact and view the predicted results. The proposed method is non-invasive, relying on capturing and analyzing the physiological signals to provide reliable and convenient monitoring of blood glucose and blood pressure levels.
Absstract of: US2025064351A1
An embodiment may provide a method for calibrating sensitivity for glucose measurement including: obtaining an offset value for determining sensitivity; determining a first sensitivity from a sensor data and a reference glucose value, based on the offset value; and determining sensitivity by adjusting the first sensitivity, wherein the determining of the sensitivity includes obtaining the first sensitivity, and determining sensitivity A by adjusting the first sensitivity according to an elapsed period of time after a sensor is inserted into a body; obtaining the first sensitivity, and determining sensitivity B by adjusting the first sensitivity by reflecting an average sensor data obtained by averaging a plurality of sensor data and an average glucose value obtained by averaging a plurality of glucose values to the first sensitivity; and determining any one of the sensitivity A and the sensitivity B as the sensitivity.
Absstract of: US2025064632A1
A fingertip warming device that can be used on either hand, will aid in warming of fingertips to help increase blood flow to the fingertips of the user for the purpose of easing the process of drawing blood, which will be used to check the user's glucose levels. The device will have warming elements either embedded in the distal end of fingertip slots/compartments or allow for the use of a heatable insert that will also reside in the distal end of the device for the purpose of warming the user's fingertips. The device will provide either flaps or a hole through which the user's fingertips can be exposed to allow for collection of a blood sample for testing glucose levels.
Absstract of: AU2023341648A1
Systems, devices, and methods for a dual analyte sensor using glucose history from a glucose sensor in combination with data from a ketone sensor to control operation of a user interface device or insulin pump are provided. In some embodiments, the systems, apparatus or methods may make use of combination of glucose history and a β-hydroxybutyrate physiological model to better predict diabetic ketoacidosis (DKA), in comparison to a prediction based on a simple high glucose threshold. In other embodiments, the systems, apparatus or method may include features for generating an estimate of the patient's medication state and/or knowledge of medication information, such as a patient with T1 diabetes mellitus (DM) using an SGLT-2 inhibitor.
Absstract of: US2025064328A1
The present disclosure includes a handheld processing device including medical applications for minimally and noninvasive glucose measurements. In an embodiment, the device creates a patient specific calibration using a measurement protocol of minimally invasive measurements and noninvasive measurements, eventually creating a patient specific noninvasive glucometer. Additionally, embodiments of the present disclosure provide for the processing device to execute medical applications and non-medical applications.
Absstract of: US2025065039A1
The disclosed embodiments are directed to a wearable automatic drug delivery device configured to provide basal-only dosing of insulin. In a primary embodiment, the wearable drug delivery device is configured to provide automatic operation and provides audible alerts and visual status indicators to the patient. In other embodiments, the patient may have some degree of control over the operation of the device by providing tapping gestures on housing of the device. In yet another embodiment, the patient may provide input and receive status from the device via an application executing on a portable computing device in wireless communication with the wearable drug delivery device.
Absstract of: US2025064353A1
A blood glucose measuring apparatus and a method of operating the blood glucose measuring apparatus are provided. The blood glucose measuring method includes extracting a measurement signal based on signals captured by a cell capsule comprising a reservoir configured to accommodate cells, including distinguishing the signals from noise; and estimating a characteristic of the cells based on the extracted measurement signal. The signals have respective oscillations that are dependent on a membrane action potential bursts phase and a membrane lower potential inter-burst phase of the cells.
Absstract of: EP4512327A1
An embodiment may provide a method for calibrating sensitivity for glucose measurement including: obtaining (S1201) an offset value for determining sensitivity; determining (S1203) a first sensitivity from a sensor data and a reference glucose value, based on the offset value; and determining (S1205) sensitivity by adjusting the first sensitivity, wherein the determining of the sensitivity includes obtaining the first sensitivity, and determining (S1205-1) sensitivity A by adjusting the first sensitivity according to an elapsed period of time after a sensor is inserted into a body; obtaining the first sensitivity, and determining (S1205-1) sensitivity B by adjusting the first sensitivity by reflecting an average sensor data obtained by averaging a plurality of sensor data and an average glucose value obtained by averaging a plurality of glucose values to the first sensitivity; and determining (S1205-2) any one of the sensitivity A and the sensitivity B as the sensitivity.
Absstract of: EP4512326A1
An embodiment may provide a method for calibrating sensitivity for glucose measurement including: obtaining (S1201) an offset value for determining sensitivity; determining (S1203) a first sensitivity from a sensor data and a reference glucose value, based on the offset value; and determining (S1205) sensitivity by adjusting the first sensitivity, wherein the determining (S1205) of the sensitivity includes obtaining one sensitivity, and determining (S1205-1) sensitivity A by adjusting the one sensitivity by reflecting an average sensor data obtained by averaging a plurality of sensor data and an average glucose value obtained by averaging a plurality of glucose values to the one sensitivity; and determining (S1205-2) the sensitivity A as the sensitivity.
Absstract of: EP4512328A2
The present invention relates to a body attachment unit for continuous glucose monitoring. The present invention provides a body attachment unit for continuous glucose monitoring, wherein: the body attachment unit is manufactured in the state in which the body attachment unit is assembled in an applicator, and thus separate additional work is minimized and the body attachment unit can be attached to the body by simply operating the applicator; in particular, a wireless communication chip is disposed in the body attachment unit so as to communicate with an external terminal, and thus simple and convenient use can be achieved without any additional work for connection of a separate transmitter and maintenance and management can also be easily performed; and the monitoring operation is started by a user's manipulation after the body attachment unit is attached to the body, and thus the user can adjust the operation start time to an appropriate point as necessary and the operation can be started in a stabilized state so as to enable more accurate glucose monitoring.
Absstract of: EP4513503A2
The subject matter disclosed herein provides methods for presenting glucose level data. Glucose data for a patient may be received. A current glucose level and a rate of change of the current glucose level may be determined based on the received glucose data. A first interface may be displayed on a screen of a device. The first interface may include a unitary icon. The unitary icon may display the current glucose level and a visualization of the rate of change. Related apparatus, systems, techniques, and articles are also described.
Absstract of: EP4512332A2
An improved sensor set is provided for sensing of a body characteristic, such as glucose. The sensor set includes a mounting base for the sensor and a connector to connect to the mounting base. The connector may contain sensor electronics for wired or wireless communication to an external monitor or display. The mounting base includes a connector fitting adapted to fit into a tubular recess in the connector, wherein the connector fitting includes a key. In some embodiments, the proximal end of the sensor folds around the key such that there are contact pads on both sides of the key. The mounting base and connector include additional features, such as pegs and prongs that allow for unique fitting of compatible mounting bases and connectors, while locking out non-compatible components.
Absstract of: EP4513510A1
This application provides a blood glucose assessment method, an electronic device, and a computer-readable storage medium. The method is applied to a wearable device, and includes: collecting vital sign data of a user in a first cycle of blood glucose assessment; performing blood glucose assessment on the user based on valid vital sign data in the vital sign data, to obtain a blood glucose assessment result corresponding to the first cycle; displaying the blood glucose assessment result corresponding to the first cycle; and automatically starting a next cycle of the blood glucose assessment. According to the technical solutions of this application, blood glucose assessment can be periodically and automatically performed, helping reduce operation complexity for the user.
Nº publicación: EP4512325A1 26/02/2025
Applicant:
SHENZHEN GOODIX TECH CO LTD [CN]
Shenzhen Goodix Technology Co., Ltd
Absstract of: EP4512325A1
A continuous glucose monitor, comprising a housing and a circuit board arranged in the housing, wherein an electronic component is carried on the circuit board; a probe assembly configured to penetrate skin and connected to the circuit board; and an auxiliary sensor connected to the circuit board and configured to detect a compressed state of the continuous glucose monitor. The continuous glucose monitor provided in the present disclosure can identify its own compressed state, thereby improving the accuracy of glucose measurement.