Absstract of: US2025391384A1
An apparatus comprising a pump configured to deliver insulin, a processor, and a user interface including a color display. Color on the display can be used to bring a user's attention to a change in status of the device or a detected change in status of the patent.
Absstract of: US2025387054A1
An encasement material that resists degradation, including yellowing. The encasement material may be used, for example, in an apparatus including a housing, circuitry at least partially within the housing, that is implanted into an animal (e.g. a human) to continuously monitor the concentrations of specific analytes, such as glucose. The encasement material allows for the efficient transmission of excitation and emission light to and from an analyte indicator in the device. The encasement material includes additives that resist and inhibit degradation of the encasement material thereby improving the longevity and life of the device. Also, methods for forming the encasement material and incorporating the encasement material within an apparatus.
Absstract of: US2025387548A1
Constituents of a liquid, such as blood, may exhibit optical signatures that allow for real-time, dynamic concentration detection. For example, concentrations of substances in aqueous solutions, including calcium, potassium, sodium, bicarbonate, chloride, magnesium, phosphate, lactate, acetate, glucose, creatinine, urea, and/or hydrogen peroxide, may be monitored during dialysis or other treatments. This is achieved by measuring real-time changes in light intensity at wavelengths corresponding to the constituents' optical signatures. Concentration may be determined using a predetermined relationship between light intensity and concentration at isolated wavelengths. Real-time monitoring enables timely treatment adjustments, improving patient outcomes.
Absstract of: US2025387561A1
The present disclosure relates to a tube connector (402) for an infusion set, for example for delivering insulin from an insulin pump. The tube connector includes a connector body (404) adapted for connection with a tube (406). The tube connector also includes opposing first and second latch arms (412, 414) resiliently joined to the connector body at flexing points (420, 422). The tube connector also includes a first lever (424) attached to the first latch arm and a second lever (426) attached to the second latch arm. The first and second levers extend alongside the first and second latch arms, respectively, such that pressing the first and second levers towards each other deflects the first and second latch arms relative to the body portion about the flexing points.
Absstract of: WO2024173658A2
An infusion system comprising: a device configured to deliver medication to a user through an infusion catheter, wherein the device includes a housing configured to receive the infusion catheter and to maintain the infusion catheter in the user after insertion; and a detachable activation mechanism for deploying the device for delivering medication to the user, wherein the detachable activation mechanism comprises a trigger and a retraction mechanism that includes an introducer needle for introducing the infusion catheter into the user, wherein the detachable activation mechanism is configured to releasably connect to the housing, wherein the detachable activation mechanism is configured to insert the infusion catheter into the user, automatically release the detachable activation mechanism from the housing responsive to activation of the trigger and automatically retract the introducer needle into the needle retraction assembly to shield the needle upon the automatic release of the detachable activation mechanism.
Absstract of: AU2025202475A1
One embodiment may provide a method of outputting blood glucose data including obtaining biometric information in response to an advertisement transmitted by a sensor transmitter, generating the biometric information as output, in the case that a communication failure occurs, indicating a data gap during a period of the communication failure, and if the communication failure is resolved, filling the data gap during a period from a time point when the communication failure is resolved to one advertisement which arrives after the communication failure is resolved. One embodiment may provide a method of outputting blood glucose data including obtaining biometric information in response to an advertisement transmitted by a sensor transmitter, generating the biometric information as output, in the case that a communication failure occurs, indicating a data gap during a period of the communication failure, and if the communication failure is resolved, filling the data gap during a period from a time point when the communication failure is resolved to one advertisement which arrives after the communication failure is resolved. pr p r c o m m u n i c a t i o n f a i l u r e i s r e s o l v e d @ pr p r
Absstract of: WO2025259242A1
The invention relates to a manually controlled manual insulin pump configuration suitable for use by diabetic individuals who have to inject with an insulin pen before each meal or high blood sugar correction dose.
Absstract of: US2025380912A1
One embodiment may provide a method of displaying a communication status in a glucose monitoring system, the method including displaying a communication status of a communication module in a terminal configured to transmit and receive data with a sensor transmitter, when the communication module is turned off, delaying a display of a communication module turn-off for one period of time by the terminal, and if the turn-off of the communication module persists for the one period of time, displaying the communication module turn-off.
Absstract of: WO2025258837A1
The present invention relates to an optical sensor and a wearable device comprising the same for non-invasively determining a concentration of blood components, for example, blood glucose and glycated hemoglobin levels. The optical sensor comprises an emitter configured to emit short-wave infrared (SWIR) radiation, an insulator with a channel transparent to the SWIR radiation, the emitter being disposed on top of the insulator and configured to emit the radiation into a biological tissue through the transparent channel, an optical concentrator made from a material with a refractive index of 1.7 or more, and a photodetector disposed in an upper part of the optical concentrator. The invention provides the possibility of non-invasive, instant or continuously monitoring of blood glucose and glycated hemoglobin levels. 2 indep. claims and 13 dep. claims, 15 figs., 2 tables.
Absstract of: AU2025201860A1
One embodiment may provide a method of providing a notification of signal loss in a glucose monitoring system, the method including, when a communication failure occurs between a terminal and a sensor transmitter, delaying a signal loss notification for a first period of time by the terminal, when the communication failure persists for the first period of time, further determining whether signal loss persists for a second period of time by the terminal, when the signal loss persists for the second period of time, generating the signal loss notification by the terminal, and outputting, by the terminal, the signal loss notification to a user. One embodiment may provide a method of providing a notification of signal loss in a glucose monitoring system, the method including, when a communication failure occurs between a terminal and a sensor transmitter, delaying a signal loss notification for a first period of time by the terminal, when the communication failure persists for the first period of time, further determining whether signal loss persists for a second period of time by the terminal, when the signal loss persists for the second period of time, generating the signal loss notification by the terminal, and outputting, by the terminal, the signal loss notification to a user.20 ar a r t o a u s e r Sensor module Sensor communicator Sensor controller Sensor storage 120 130 140 Outputter Communicator Controller Storage 220 230 240 ar a r
Absstract of: EP4664482A2
The present disclosure relates to a method for transmitting or receiving biometric information in a continuous glucose monitoring system and, more specifically, to a method for transmitting or receiving biometric information, in which: when a sensor transmitter generates a transmission packet, the transmission packet is generated to include a generation identifier for identifying the transmission packet or biometric information according to a generation order of the transmission packet or the biometric information, and therefore the biometric information may be transmitted or received without a loss thereof via the generation identifier; and a transmission packet or biometric information, which a communication terminal has failed to receive, is correctly determined on the basis of a packet generation identifier or a total number of transmission packets, so that only biometric information or a transmission packet, which has failed to be received between the sensor transmitter and the communication terminal, may be transmitted or received in a distinguished manner.
Absstract of: EP4663120A1
One embodiment may provide a method of displaying a communication status in a glucose monitoring system, the method including displaying a communication status of a communication module in a terminal configured to transmit and receive data with a sensor transmitter, when the communication module is turned off, delaying a display of a communication module turn-off for one period of time by the terminal, and if the turn-off of the communication module persists for the one period of time, displaying the communication module turn-off.
Absstract of: CN120787146A
Intravascular artificial pancreatic devices and methods of making the same are disclosed herein.
Absstract of: WO2025255026A1
A device for delivering medication to a user, the device configured to be mounted to the user, the device comprising: (a) a baseplate and a housing configured to engage the baseplate to form an interior therein; (b) a platform mounted to the baseplate within the interior, the platform configured to support a micropump having an inlet port for communicating with a reservoir and an outlet port for communicating with a cannula for delivering the medication to the use.
Absstract of: WO2025253234A1
A system and method for non-invasive blood glucose level determination and proactive management are disclosed. A sensing device comprises a capacitance-to-digital converter (CDC) sensor, featuring an active shield electrode and single-ended mode operation, to measure capacitance variations indicative of net body charge modulation by systemic physiological activity correlated with blood glucose. The device also includes at least one skin conductance sensor. A processor determines blood glucose levels from combined CDC and skin conductance data, optionally using machine learning. Further, a proactive artificial intelligence (AI) system, employing supervised and reinforcement learning models, analyzes real-time and historical data to predict blood glucose trajectories and the likelihood of future dysregulation. Crucially, the AI dynamically generates a personalized schedule of recommended actions (e.g., relating to diet, exercise, or medication timing) for managing the subject's blood glucose, providing alerts and the action plan to enhance diabetes self-management.
Absstract of: US2025375573A1
A simplified insulin pump allows diabetics to identify routine patterns in their daily lifestyle that provide a generally accurate typical pattern of activity and meals. An infusion regimen can be programmed into the pump that generally correlates with this typical pattern to provide a viable treatment option for a diabetic without the need for specific and precise matching of insulin to carbohydrate consumption or activity level.
Absstract of: US2025375574A1
A method for improving blood glucose control of a hybrid controller meal and exercise announcement by substituting patient-initiated meal boluses of said hybrid controller by an automatic insulin correction signal without retuning of said hybrid controller, and by incorporating rescue carbohydrates suggestion for hypoglycemia mitigation, comprising the steps of measuring a plasma glucose (G(t)) signal by means of a continuous glucose monitor (CGM), calculating a glucose level (Ĝ(t)) by using a glucose-insulin model; computing a disturbance term d(t), generating a virtual signal uIMC(t), for mitigating the effect of d(t) on the output, by means of an IMC filter Q(s) and converting the virtual signal uIMC(t) into three feed forward actions: insulin infusion, rescue carbohydrate suggestion, and insulin-on-board reduction.
Absstract of: US2025377296A1
A process and sensor system with particular control of polarization of the interrogating light beams useful for determining a concentration of a targeted molecule M (such as glucose) within a given time period in a liquid sampling matrix through use of a Direct Infrared Laser Absorption Spectroscopy Technique.
Absstract of: WO2025254973A1
A computational continuous glucose monitoring system is disclosed which integrates a biocompatible phosphorescence-based insertable sensor and a custom-designed phosphorescence imager (PI). This PI captures phosphorescence lifetime images of an insertable sensor through the skin where the lifetime of the emitted phosphorescence signal is modulated by the local concentration of glucose. The lifetime images acquired through the skin are processed by neural network-based models for misalignment-tolerant inference of glucose levels, accurately revealing normal, low (hypoglycemia) and high (hyperglycemia) concentration ranges. Using a 1-mm thick skin phantom mimicking the optical properties of human skin, in vitro testing of the PI using glucose-spiked samples yielded 88.8% inference accuracy, also showing resilience to random and unknown misalignments within a lateral distance of ~4.7 mm. Lateral misalignments beyond 5 mm prompted user intervention for re-alignment.
Absstract of: WO2024160808A1
The present disclosure relates to highly integrated sensor devices such as implantable devices, continuous monitoring devices and portable smart devices for determining a physiological parameter in a bodily fluid and/or tissue of a subject. Further, the present disclosure relates to methods for determining a physiological parameter in a bodily fluid and/or tissue of a subject.
Absstract of: WO2025245938A1
A personalized closed-loop infusion system and method. Relevant information of patients is uploaded to a cloud server (104), and is grouped on the basis of identifiable features of the patients; the relevant information of different patients, such as blood glucose data records and insulin infusion data records, is compared in a same group; and when the relevant information of the patients is the same or similar, insulin algorithm parameters of patients with well-controlled blood glucose can be used for modifying an insulin algorithm of patients with poorly-controlled blood glucose, and a closed-loop artificial pancreas system can quickly obtain personalized insulin algorithms suitable for the patients without the need of long-period learning of physiological characteristics and lifestyle habits of the patients, thereby benefiting diabetes treatment of the patients.
Absstract of: US2025366741A1
One embodiment may provide a method of providing a notification of signal loss in a glucose monitoring system, the method including, when a communication failure occurs between a terminal and a sensor transmitter, delaying a signal loss notification for a first period of time by the terminal, when the communication failure persists for the first period of time, further determining whether signal loss persists for a second period of time by the terminal, when the signal loss persists for the second period of time, generating the signal loss notification by the terminal, and outputting, by the terminal, the signal loss notification to a user.
Absstract of: WO2025245624A1
It is provided an insulin formulation comprising insulin and antimicrobial excipients for use in insulin pumps, connected to subcutaneous tissue via a catheter, a method also known as continuous subcutaneous insulin infusion, wherein the antimicrobial excipient inhibits growth of bacteria in insulin formulations and biofilm bacterial population formation on the internal surfaces of a catheter, allowing extending the time of use of the catheter.
Absstract of: WO2025249486A1
Provided are a program, a system, an information processing device, a server, and a method capable of executing a game in which a game effect occurs on the basis of continuously measured biological information. There is provided a program to be executed by a computer including a processor and a memory, the program causing the processor to execute a step of acquiring continuous blood glucose level data of a user associated with time information including an acquisition time prior to an acquisition time point, and a step of generating a predetermined game effect on the basis of the continuous blood glucose level data within a predetermined time period.
Nº publicación: US2025372257A1 04/12/2025
Applicant:
US GOV AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS [US]
United States Government As Represented By The Department of Veterans Affairs
Absstract of: US2025372257A1
Methods, systems, and apparatuses for modeling and determining of an insulin elimination rate in individuals are described. One or more physiological measurements associated with an individual may be determined and applied to a multi-compartment model. One or more physiological parameters, including an insulin elimination rate, may be determined based on applying the one or more physiological measurements to the multi-compartment model.