Resumen de: WO2026198389A1
Disclosed is a method of patient care based on a digital twin that includes comparing a determined first parameter and a predicted first parameter. The determined first parameter is based on a signal and the predicted first parameter is based on the second parameter. If the comparing is false, that is, the determined first parameter does not correspond with the predicted first parameter, then the method includes defining a first condition.
Resumen de: US20260290582A1
0000 A system and method for performing Internet-of-Things (IoT)-based detection of Premature Ventricular Contractions (PVC) arrhythmias includes electrocardiography (ECG) signal acquisition circuitry attached to a patient's body to acquire an ECG signal from the patient. The system includes IoT-based signal transmission circuitry using IoT communication to transmit the ECG signal to a Fog-network-based signal processing circuitry. The Fog-network-based signal processing circuitry uses a Fog network to apply a modified Pan and Tompkins algorithm to extract ECG features in frequency domain and time domain from the ECG signal; determine whether the patient has PVC arrhythmias, based on the extracted ECG features, provide an alert to the patient and a healthcare team upon determining that the patient has the PVC arrhythmias. The extracted ECG features include QRS complex durations, R-peaks, R-R intervals, an average of the R-R intervals, and an average deviation of the R-R intervals.
Resumen de: DE102025137937A1
Emotionsbasiertes Datenanalysesystem zur Benutzeremotionsüberwachung (1000), aufweisend: einen Datenspeicher (210), der einen vordefinierten Fragensatz (211-1 bis 211-N) und ein Emotionsmuster (212-1 bis 212-N) einer gesunden Person speichert, eine Szenariosteuereinrichtung (220), die Fragen sequenziell ausführt und einen Antworterlangungs-Startzeitpunkt und einen Antworterlangungs-Endzeitpunkt eines Benutzers (100-1) steuert, eine Vorverarbeitungsvorrichtung (230), die Elemente von Daten erhält, die eine Emotion des Benutzers (100-1) anzeigen, um vorverarbeitete Daten zu erzeugen, eine Individuelle-Emotion- Extraktionsvorrichtung (240), die eine Valenz und Erregung vorhersagt, eine Endgültige-Emotion-Ermittlungsvorrichtung (250), die vorhergesagte Werte der Valenz und der Erregung analysiert und den berechneten Wert als eine endgültige repräsentative Emotion primär extrahiert, eine Benutzeremotionsmuster-Analysevorrichtung (260), die die primär extrahierte endgültige repräsentative Emotion mit dem Emotionsmuster (212-1 bis 212-N) einer gesunden Person vergleicht und eine endgültige repräsentative Emotion sekundär extrahiert, und eine Anormale-Daten-Speicher-Servervorrichtung (310), die die sekundär extrahierte endgültige repräsentative Emotion empfängt und speichert.
Resumen de: DE102025111075A1
Die vorliegende Erfindung betrifft ein Verfahren zur Herstellung von dopaminergen neuronalen Organoiden (d-NOs) mit Nachweis der Dopaminfreisetzung in biologisch wirksamen Konzentrationen. Darüber hinaus umfassen d-NOs neben dopaminergen Neuronen auch funktionell miteinander verbundene GABAerge, glutamaterge und cholinerge Neuronen sowie Gliazellen, wodurch sie zu einem multizellulären Organoid mit einer für das Mittelhirn repräsentativen Zellzusammensetzung und Funktion werden. Daher zeigen die d-NOs der Erfindung eine komplexe Regulation dopaminerger Neuronen durch verwandte exzitatorische und inhibitorische Neuronen, was auf Kontrollmechanismen hindeutet, die beispielsweise eine Überproduktion und Freisetzung von Dopamin verhindern können. Die Erfindung bezieht sich auch auf die n-NOs als Implantat oder zur Verwendung bei der Behandlung der Parkinson-Krankheit. Darüber hinaus bezieht sich die Erfindung auf die Verwendung der d-NOs für Wirkstoffscreenings.
Resumen de: US20260292026A1
0000 A medical-device LoRa communication system includes a LoRa communication module coupled to a host medical device or patient-associated medical device. The module obtains medical-device, physiological, alarm, device-status, or device-identity data and generates an encrypted LoRa packet having a relay-readable header, protected clinical-context metadata, and an encrypted payload. One or more LoRa relay nodes forward the packet toward an authorized gateway using the relay-readable header without decrypting the payload or accessing the protected clinical-context metadata in readable form. The authorized gateway validates packet information against authorization records and patient-context or device-context records before downstream clinical release. When validation fails, downstream clinical routing is prevented. When validation succeeds, the gateway decrypts the payload, binds the data to a validated context record, and makes the data available to an authorized electronic medical record system, medical device data system, medical data governance system, or other downstream system.
Resumen de: DE102025111350A1
Gegenstand der Erfindung ist eine dentale geschichtete Prothese, umfassend mindestens einen inneren Zahnbereich und mindestens eine, den inneren Zahnbereich teilweise bis vollständig umgebende Zahnschicht, und optional mindestens eine Zahnhalsschicht sowie ein Verfahren zu deren Herstellung als auch ein Computerprogrammprodukt zur Herstellung der Prothese.
Resumen de: US20260290207A1
0000 Airway models and sets of airway models capture anatomical morphologies of mouth-throat geometries. The models capture intersubject variability. In addition, a method of predicting deposition of a nebulized hygroscopic aerosol in at least one pediatric oral airway involves determining or receiving one or more airway geometries from the one or more medical images including at least one characteristic dimension of an oral airway and an airway volume; determining or receiving one or more delivery conditions for the nebulized hygroscopic aerosol; calculating multiple nondimensional parameters such as Tidal Volume/airway volume ratio (TV/V), Stokes (Stk) number, Reynolds (Re) number, and Schmidt (Sc) number; and determining deposition in the oral airway using the TV/V, Stk, Re, and Sc numbers.
Resumen de: US20260283763A1
0000 A method of making and shipping or delivering an impression of a gum facing portion of a dental appliance includes pressing the gum facing portion of the dental appliance against a putty in an impression container. The method also includes allowing the putty to harden to make the impression and removing the dental appliance from the impression after the putty has hardened. The impression container with the impression of the gum facing portion of the dental appliance is then shipped or delivered.
Resumen de: DE102025110966A1
Die vorliegende Erfindung betrifft eine Muffel, einen Aufbau und ein Verfahren zur Herstellung eines Dentalbauteils, insbesondere eines Zahnersatzes oder eines - teilersatzes. Die Muffel weist zumindest eine Kavität auf, die eine Negativform des herzustellenden Denktalbauteils ist, und zumindest einen Kanal, der mit der Kavität in Verbindung steht. Die Muffel weist eine erste Stirnseite und eine zweite Stirnseite auf, die an einander gegenüberliegenden Enden der Muffel angeordnet sind, wobei die erste Stirnseite eine Öffnung aufweist, die mit dem Kanal in Verbindung steht, und wobei an die erste Stirnseite zumindest eine Erhebung angeformt ist, die sich von der ersten Stirnseite erstreckt.
Resumen de: WO2026180764A1
The invention relates to a bioink for 3D printing of a scaffold (1) suitable for corneal tissue regeneration, composed of sodium alginate, aldehyde hyaluronic acid, N,O-carboxymethyl chitosan and collagen I, where the collagen I undergoes a preliminary neutralisation process using sodium hydroxide. The present invention also describes a method for the 3D printing of a scaffold (1) suitable for corneal tissue regeneration and a method for sterilising same using ethylene oxide (EtO).
Resumen de: WO2025104550A1
The invention relates to a radiation-curable composition for additive-manufacturing processes, the composition comprising (meth)acrylate component A1 comprising a polyalkylene oxide backbone, with at least two (meth)acrylate moieties, not comprising a urethane moiety, and having a molecular weight Mw of at least 2,000 g/mol, (meth)acrylate component A1 being present in an amount of 50 to 85 wt.%, (meth)acrylate component A2 with at least two (meth)acrylate moieties, comprising in addition at least two urethane moieties, and having a molecular weight Mw of at most 1,000 g/mol, (meth)acrylate component A2 being present in an amount of 5 to 20 wt.%, (meth)acrylate component A3 with only one (meth)acrylate moiety, and having a molecular weight of at most 500 g/mol, (meth)acrylate component A3 being present in an amount of 5 to 20 wt.%, photo-initiator, and optionally stabilizer, wt.% with respect to the amount of the whole composition. The invention also relates to a process of producing an elastomeric 3-dim article by processing the radiation-curable composition, an elastomeric 3-dim article obtainable by such a process.
Resumen de: WO2025104746A1
The present disclosure relates tobiodegradable and radiopaque polymer of formula I. More specifically, the present disclosure pivots on development of tracheal splint and self- expandable stent that is radiopaque and promotes the growth, proliferation and functioning of various types of cells – chondrocytes, epithelial cells and endothelial cells.
Resumen de: EP4811293A1
The present disclosure is to a computer-implemented method for flattening a digital 3D mesh representing a dental object. The method comprises obtaining the digital 3D mesh. The method comprises determining a circumferential mesh boundary in the digital 3D mesh, wherein the mesh boundary comprises multiple boundary vertices surrounding multiple inner vertices. The method comprises determining a target shape with a circumferential target boundary, wherein the target shape is planar. The method comprises for each vertex of the boundary vertices, performing coherent mapping to an anchor point on the target boundary corresponding to the respective vertex. The method comprises for each vertex of the boundary vertices, translating the respective boundary vertex to its corresponding anchor point on the target boundary. The method comprises flattening the inner vertices to the target shape to generate a flattened mesh based on the anchor points.
Resumen de: EP4811350A1
An assistance control apparatus (3) includes: a mental state data generation unit (63) that generates mental state data indicating a mental state of a user, the mental state data being generated from physical state data indicating a physical state obtained based on sensing on a body of the user; and controls a control object in a space for communication of the user based on the mental state data of the user.
Resumen de: EP4809968A1
0001 Es wird ein computer-implementiertes Verfahren zum Bestimmen einer Soll-Außenfläche (46) einer Zahnschiene beschrieben. Dabei wird ein virtuelles Zahnschienenrohlingmodell (30) basierend auf einem virtuellen Zahnmodell (28) erzeugt. Ferner wird das virtuelle Zahnschienenrohlingmodell (30) basierend auf Materialdaten erzeugt, die wenigstens eine Eigenschaft eines Materials beschreiben, aus dem die Zahnschiene hergestellt werden soll. Alternativ wird das virtuelle Zahnschienenrohlingmodell (30) erhalten. Zusätzlich wird ein virtuelles Antagonistenmodell (42) erhalten. Außerdem wird die Soll-Außenfläche (46) der Zahnschiene basierend auf dem virtuellen Zahnschienenrohlingmodell (30) und dem virtuellen Antagonistenmodell (42) bestimmt. Auch wird ein Verfahren zum Herstellen einer Zahnschiene sowie eine damit erhaltene Zahnschiene vorgestellt. Zudem werden eine Vorrichtung zur Datenverarbeitung, ein Computerprogramm und ein computerlesbares Medium präsentiert.
Resumen de: EP4811380A1
0001 A communication system (1) includes a detection control device (6) to perform sensing of a body of a user, and an assistance control device (3) to communicate with the detection control device (6) and control a target device. The detection control device (6) includes a mental state data generation unit (63) to generate mental state data indicating a predetermined mental state of the user based on physical state data indicating a predetermined physical state, the physical state data being obtained based on the sensing of the body of the user, and a transmission unit (60) to transmit the mental state data to the assistance control device (3) based on the mental state data of the user. The assistance control device (3) includes a control unit (34, 37) to control a specific device in a communication space of the user among target devices including the target device based on the mental state data transmitted from the detection control device (6).
Resumen de: EP4811385A1
0001 Disclosed is a computer-implemented method for automatically designing a dental restoration for placing in a dentition of a patient, the method comprising the steps of: obtaining digital three-dimensional (3D) surface data representing a surface of the dentition of the patient in 3D space, wherein the surface comprises a preparation surface configured to receive the dental restoration; pre-processing the 3D surface data to generate a discretized 3D model comprising granularity elements defining a discretized representation of at least a part of the 3D surface data, wherein the at least a part of the 3D surface data comprises the preparation surface; pre-processing the discretized 3D model to generate an encoded representation of the discretized 3D model, wherein the encoded representation comprises the granularity elements, and each granularity element is encoded with at least distance information from the point to at least one functional surface; processing the encoded representation by using a trained model configured to process the encoded representation; receiving an output of the processing from the trained model, wherein the output comprises at least a part of the dental restoration; and automatically designing the dental restoration based on the received output.
Resumen de: WO2025102118A1
The present disclosure relates to implants for teeth and bone. The implants are prepared from a polymer of the poly (aryl ether ketone) family, preferably poly ether ketone (PEK), and are activated with plasma to improve integration with teeth and bone. Methods and kits related to use of the implants are also disclosed.
Resumen de: WO2025103994A1
The present invention relates to a dental or surgical handpiece (1) formed by a head (10) and a gripping handle (11), each provided with at least one integrated internal duct (2) selected from a pneumatic duct (20), a light transmission duct (23), and a blind duct (24) suitable for housing one or more electronic sensors (5), characterised in that at least one element selected from an internal shell (111) of the handle (11) and the head (11) is made by 3D printing in metal and contains the pneumatic duct (20) and/or the light transmission duct (23) and/or the blind duct (24) as an integrated internal duct (2) in a single unit.
Resumen de: EP4811370A1
0001 To provide a system and method that can effectively utilize biometric data obtained in the daily life of the user for the user's maintenance and improvement of the health, and can provide further customized user-friendly health advice for the user, a system for providing health advice for a user includes: a structure installed in a facility and including a sensor that continuously collects biometric data of the user, an analyzing device so configured as to determine the health condition of the user by performing analysis of the biometric data collected by the sensor, a program generating device so configured as to generate a health promotion program in response to the user by using the results of the determination of the health condition, and an advice generating device so configured as to input the determined health condition, the generated health promotion program, and additional information relating to the user into a large language model to obtain health advice for the user.
Resumen de: EP4809909A2
0001 Disclosed are systems, methods, and articles for determining compatibility of a mobile application and operating system on a mobile device. In some aspects, a method includes receiving one or more data values from a mobile device having a mobile medical software application installed thereon, the data value(s) characterizing a version of the software application, a version of an operating system installed on the mobile device, and one or more attributes of the mobile device; determining whether the mobile medical software application is compatible with the operating system by at least comparing the received data value(s) to one or more test values in a configuration file; and sending a message to the mobile device based on the determining, the message causing the software application to operate in one or more of a normal mode, a safe mode, and a non-operational mode.
Resumen de: EP4810168A2
0001 A droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, and ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a stream of droplets having an average ejected droplet diameter within the respirable size range, e.g, less than about 5 µm, so as to target the pulmonary system of the user.
Resumen de: US20240274283A1
0000 A method is provided for managing a gas delivery device by a server. The method includes receiving a request to provision a serial number of a PCB from a manufacturing application executing at a manufacturer; providing the serial number and a test firmware to the manufacturer; providing a product firmware to the manufacturing application for installation into the gas delivery device; receiving encrypted data from a gas delivery gateway that is configured to receive performance information from the gas delivery device; decrypting the encrypted data to yield the performance information and storing the performance information in a historical repository; receiving one or more actions that are performed at a servicing application; logging each of the one or more actions in the historical repository; and providing at least one token or data to the servicing application for each of the one or more actions.
Resumen de: CN122786131A
本发明公开了一种用于骨修复的钛网定位与骨粉塑形装置及其制作方法。本发明的钛网定位与骨粉塑形装置包括钛网和定位导板,定位导板的骨粉塑形部上的凸起插入到钛网的空隙内,从而定位导板与3D打印钛网模型结合在一起,术中医生将骨粉置于骨缺损区,然后将结合在一起的定位导板与3D打印钛网模型置入骨缺损区,由于定位导板两侧的定位部与余留天然牙及颌骨贴合的解剖标记结构匹配,即定位部的形状与骨缺损区两侧的结构相匹配,从而确保能3D打印钛网能准确地置入骨缺损区,然后通过固定钉将3D打印钛网与骨粉固定,从而完成钛网的固定。本发明集成定位和塑形功能,减少术中步骤,钛网和骨粉能快速、稳定地定位于患者的骨缺损区域。
Nº publicación: CN122785938A 22/09/2026
Solicitante:
湖南科迈森医疗科技有限公司
Resumen de: CN122785938A
0001 本发明提供一种基于压力检测预测的宫腔镜导航方法及宫腔镜系统,涉及智能控制技术领域,所述方法包括:按照预设的压力探测序列向宫腔内依次施加多个不同幅度的压力探测阶梯,并同步获取压力响应数据;根据压力探测序列的时序结构对压力响应数据进行分段处理,得到各压力探测阶梯对应的压力响应分段数据;基于压力响应分段数据,计算得到表征宫腔灌注系统动态响应特性的压力传导敏感系数。本发明通过多阶梯压力探测量化宫腔压力传导特性并自适应补偿压力偏差、安全约束灌注流速,同时结合流速与压力参数推演宫腔容积变化及镜体前端偏移,将压力监测数据转化为手术导航信息,兼顾宫腔压力调控精度、术中操作安全性与宫腔镜实时空间导航能力。