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一种脊柱矫形测量装置

Resumen de: CN122350686A

本发明涉及脊柱矫形技术领域，特别是涉及一种脊柱矫形测量装置。该装置包括支撑立板、电机丝杆导轨、支撑臂、电动线性模组、靠背板及测力组件，支撑立板上设限位开关，电动线性模组驱动靠背板升降，配合可调扶手实现患者姿态限位；电机丝杆导轨、手动丝杆导轨及螺纹丝杆协同调节测力传感器位置，精准对位脊柱待测点；装置可精准采集矫形力数据并传输至外部系统，为个性化脊柱矫形器设计生产提供实测依据。本装置定位精准、测力可靠，适配不同体型患者，操作便捷，有效提升青少年特发性脊柱侧凸矫形测力精度与效率。

一种基于冷冻3D打印的多孔聚醚醚酮/陶瓷复合材料及其制备方法

Resumen de: CN122356557A

本发明提供了一种基于冷冻3D打印的多孔聚醚醚酮/陶瓷复合材料及其制备方法，将PEEK粉末与陶瓷粉末均匀分散于溶剂中，形成复合浆料；将复合浆料在低温冷冻平台上逐层打印，形成以冰晶为模板的预制体；随后经冷冻干燥移除冰晶，再通过程序化的热处理使PEEK颗粒固结，最终获得具有预设三维多孔结构的复合支架。本发明利用冷冻打印过程中冰晶的定向生长与升华，一步成型高精度、高连通性的仿生多孔结构，并实现了陶瓷材料在PEEK基体中的均匀、稳固复合，使支架同时具备较大的孔隙率和良好的力学性能，解决了传统高温发泡加工无法兼容热敏感陶瓷、以及多孔结构调控精度不足的问题。该制备工艺灵活，适用于制造个性化多孔结构与材料。

一种磷酸钙-聚己内酯复合材料支架及其制备方法与应用

Resumen de: CN122351600A

本发明提供了一种磷酸钙‑聚己内酯复合材料支架及其制备方法与应用，其中磷酸钙‑聚己内酯复合材料的制备原料包括聚己内酯、β‑磷酸三钙和羟基磷灰石，所得到的复合支架具有促免疫和调控骨再生的功能。本发明的磷酸钙‑聚己内酯复合材料支架的制备方法是先形成羟基磷灰石/聚己内酯复合薄膜，经破碎后与β‑磷酸三钙再度形成复合溶液的方式，所得到的3D打印复合支架不仅具有良好的机械强度和生物相容性，还同时具有诱导干细胞增殖和成骨分化、诱导巨噬细胞的再生分型极化的功能，可用于调控免疫细胞反应，诱导产生有利于骨生成的骨免疫微环境，进而提升骨再生效果，可用于组织缺损的修复和再生。

一种选区激光熔化的镁合金输尿管支架及制备方法

Resumen de: CN122351603A

本发明涉及医疗器械技术领域，公开了一种选区激光熔化的镁合金输尿管支架及制备方法，包括多孔网状结构，支架表面生成有一层均匀致密的磷酸镁转化膜。支架由选区激光熔化专用镁合金复合粉末制成，粉末由钇、钆、钕、锌、锰、锆和高纯镁原料制成。制备方法包括建立患者三维模型并切片处理；采用复合粉末逐层铺粉并熔化得到毛坯；将毛坯分离并进行打磨；打磨后置于热处理炉中依次进行固溶处理和时效处理；浸没于磷酸水溶液中发生钝化反应原位生成转化膜，最后灭菌包装。通过基体成分设计配合选区激光熔化成型技术与表面钝化膜处理，获得了降解速率可控、抗结壳且具备初期力学支撑能力的镁合金输尿管支架。

具有多层级梯度氮化钛耐磨陶瓷层的钛合金关节植入体及其制备方法

Resumen de: CN122351574A

本发明公开了一种具有多层级梯度氮化钛耐磨陶瓷层的钛合金关节植入体及其制备方法，方法包括对植入体表面进行清洁打磨，并采用三维光学扫描轮廓生成路径；在氮气‑氩气混合气氛箱内，通过分阶段调控激光功率、扫描速度、光斑尺寸及氮气体积分数等工艺参数，利用激光重熔扫描依次构建成分梯度过渡层、深度重熔强化层、浅度重熔强化层及表面致密耐磨层，实现从钛合金基体到表层氮化钛陶瓷的成分、组织与性能连续梯度分布的一体化原位合成。本发明可在保留骨接触面仿生多孔结构的同时，在关节摩擦面形成厚度约200μm、显微硬度≥25GPa、表面粗糙度Ra＜0.2μm的高结合强度梯度氮化钛陶瓷层，显著提升植入体的耐磨性、生物相容性与长期服役稳定性。

带过滤的液滴输送装置

Resumen de: WO2025122635A1

An aerosol delivery device including a liquid supply, an electronically actuated droplet ejector in fluid communication with the liquid supply, and filter media or inertial filter points between the ejector and a droplets outlet to reduce the droplet size distribution of ejected droplets to smaller droplets exiting the droplets outlet.

排汗传感器数据分析

Resumen de: WO2025032589A1

A system and methods for physiological analysis and feedback includes multiple sensors configured to be worn on a user's skin and to measure, in real time, perspiration data indicative of levels of multiple respective perspiration components, and one or more processors configured to receive the perspiration data in real-time. The processors apply the perspiration data to a biomarker correlation model trained to correlate input including the multiple perspiration components, together with user specific data including age, weight, and gender, with output including multiple physiological parameters. Two of the multiple physiological parameters may be oxygen consumption (VO2) and carbon dioxide elimination (VCO2). Additionally, a risk of coronary artery blockage may be calculated by applying the calculated VO2 levels to a heart risk correlation model trained to correlate VO2 levels with levels of risk of coronary artery blockage.

一种个性化穴位刺激系统的全流程闭环控制方法

Resumen de: CN122351012A

0001 本发明涉及医疗器械技术领域，公开了一种个性化穴位刺激系统的全流程闭环控制方法，包括以下步骤：S1、患者诊疗建档与个性化护具制备阶段；S2、医师辨证处方生成阶段；S3、处方指令下发与刺激执行阶段；S4、治疗数据实时采集与回传阶段；S5、医师疗效评估与辨证复核阶段；S6、处方动态优化与闭环迭代阶段；本发明通过定制化的护具制备工艺与内置隔振结构设计，实现了刺激单元与目标穴位的对位，避免了多刺激单元工作过程中的相互干扰，提升了穴位刺激的精准性与独立性，同时通过多通道独立控制与精细化协同时序设计，可完整实现中医穴位配伍的协同治疗逻辑与传统补泻手法的数字化模拟，充分贴合中医辨证施治的核心诊疗理念。

SHAPED ORGANOID COMPOSITIONS AND METHODS OF MAKING SAME

Resumen de: US20260193617A1

0000 Disclosed herein are organoid compositions that are manipulated to form shaped or elongated morphologies that more closely resemble native organ structures. These shaped organoids are advantageous for purposes such as studying organellar organization and for transplants compared to unformed organoids. Also disclosed herein are methods of producing said shaped or elongated organoid compositions.

SCAFFOLDS FOR USE IN TISSUE ENGINEERING AND METHOD FOR PREPARING SCAFFOLDS

Resumen de: US20260192017A1

0000 The present disclosure is directed to a degradable 3D-printable scaffold for use in tissue engineering, which scaffold has a combined gradient and staggered structure. Further provided is a medical device for use in tissue engineering, comprising such a scaffold. The present disclosure also provides a method for preparing a scaffold by additive manufacturing, e.g. 3D-printing, a method for in vivo tissue engineering, use of the scaffold in an in vitro cell culture system, in an in vitro method for culturing of cells and/or in an in vitro method for regenerating tissue. Also provided is a scaffold and a medical device for use in a method for in vivo tissue engineering. Further disclosed is a novel degradable copolymer of ε-caprolactone and p-dioxanone, which can be printed without degradation and which is particularly suitable for use as scaffold material in the scaffold and method according to the present disclosure.

METHOD FOR MAKING IMPLANT HAVING A WEB STRUCTURE

Resumen de: US20260191659A1

Various methods for making an implant for interfacing with a bone structure are described. The implant includes a web structure having a space truss. The implant may be made according to a three-dimensional model of the implant. The implant may be made by applying multiple layers of a biocompatible material to a support (e.g., a support structure) in a layer-by-layer process. The web structure may have a plurality of struts joined at nodes where the web structure is configured to interface with human bone tissue.

ALIGNER MANUFACTURING SYSTEMS

Resumen de: US20260192507A1

A system is configured to manufacture multiple aligners simultaneously. The system includes a plate configured to secure first and second molds that are based on first and second digital models associated with a dental arch of a patient corresponding to first and second stages of an orthodontic treatment. The system further includes a heater configured to heat a sheet of plastic to generate a heated sheet and a mask configured to surround the sheet of plastic during heating of the sheet of plastic to minimize heat transfer to other sheets of plastic and to substantially provide a thermal seal between the heater and the sheet of plastic. The system further includes a thermoforming chamber configured to simultaneously thermoform the heated sheet over the first and second molds to form first and second aligners shaped to fit the dental arch at the first and second stages of the orthodontic treatment.

TEXTILE SEAL-FORMING STRUCTURE WITH MULTIPLE CURVATURES

Resumen de: AU2026204772A1

A patient interface including a seal-forming structure with a textile membrane that has at least one hole such that the flow of air at a therapeutic pressure is delivered to at least an entrance to the patient’s nares and/or an entrance to the patient’s mouth. The seal-forming structure is constructed and arranged to maintain the therapeutic pressure in a cavity of a plenum chamber throughout the patient’s respiratory cycle, in use. The textile membrane includes a first portion that is held in a relaxed state and a second portion that is held in a taut state. The taut state of the second portion is configured to allow the seal-forming structure to include a three-dimensional shape that has multiple curvatures. un u n

METHODS AND SYSTEMS FOR DYNAMIC CORONARY ROADMAPPING

Resumen de: US20260191490A1

Methods and systems are provided for dynamically visualizing an object of interest that includes part of the vasculature of a patient, which employ a 3D model of the object to generate at least one roadmap that includes information that characterizes properties of the object (such as centerlines, contours, and an image mask. Reference location(s) corresponding to the roadmap(s) are determined for an interventional device used to treat the object. In an online phase, non-contrast-enhanced x-ray image data of the object are obtained and processed to determine location of the interventional device in the image data, and a particular roadmap is selected or accessed. The reference location corresponding to the particular roadmap and the determined location of interventional device are used to transform the particular roadmap. A visual representation of the transformed roadmap is overlaid on the image data for display.

CONSUMABLE EXTRUSION CONTROL SYSTEM, METHOD AND DEVICE

Resumen de: US20260191629A1

0000 A consumable extrusion control system, a consumable extrusion control method and a consumable extrusion control device are provided. The consumable extrusion control system includes: a main body; a plurality consumable chambers coupled to the main body through respective pipelines; a plurality of first driving assemblies arranged on the respective pipelines for the consumable chambers, and configured to provide a driving force for consumables in the consumable chambers; and a control unit arranged at the main body, and configured to control and switch a corresponding first driving assembly to operate, to deliver the consumable from a corresponding one of the consumable chambers to the main body.

SYSTEMS AND METHODS FOR CONTACTLESS MONITORING

Resumen de: WO2026148102A1

A system and method for monitoring a health status of a patient using one or more radar sensors placed in an environment containing the patient. A processor controls the radar sensors to emit radio waves and measures reflection data including reflected radio waves. The processor processes the reflection data to determine motion state data characterizing position and velocity, isolates motion state data associated with human movement patterns to generate tracked motion state data, and aggregates the tracked motion state data to generate aggregate motion data. Machine learning algorithms process the aggregate motion data to determine health status including fall detection, behavior identification, and characterization of Alzheimer's disease, dementia, Parkinson's disease, fall risk, and sundowning. The system tracks aggregate motion data longitudinally over time and generates reports based on health status.

SYSTEM AND METHODS FOR A LABOR COACH ALGORITHM

Resumen de: US20260191458A1

0000 Methods and systems are provided for receiving labor-related data for one or more previous contractions of a patient, the labor-related data at least comprising data obtained with one of a tocodynamometer, an IUPC, and an EHG recording system, predicting labor-related data for a next contraction based on the labor-related data for one or more previous contractions, generating one or more visual indicators and one or more audio indicators based on output from a labor prediction model, the output from the labor prediction model being generated by entering the received labor-related data for the one or more previous contractions into the labor prediction model, the predicted labor-related data, and user input into the labor prediction model, and displaying the one or more visual indicators to a display device that is visible to the patient and outputting the one or more audio indicators to the patient.

EMERGENCY ALERT MANAGEMENT

Resumen de: US20260191454A1

Systems and methods to improve resource utilization in ambulatory patient monitoring are disclosed, including detecting a critical event using the physiologic information, transitioning the ambulatory medical device from a long-term ambulatory monitoring mode to a critical response mode, and controlling, in the critical response mode, transmission of an advertising packet and information about the detected critical event to a remote device in a continuous listening mode or transition of a communication circuit of the ambulatory medical device to a listening mode to receive an advertising packet of the remote device in a continuous advertising mode to transmit a connection response and information about the detected critical event to the remote device to improve resource utilization of the ambulatory patient monitoring.

WEARABLE DEVICE, METHOD, AND STORAGE MEDIUM FOR PROVIDING SCREEN GENERATED FROM TRAINED MODEL

Resumen de: WO2026146885A1

This wearable device may comprise at least one sensor, a display, a memory for storing instructions, and at least one processor. The instructions, when executed individually or collectively by the at least one processor, may cause the wearable device to: display a first screen of a watch face through the display; obtain input data through the at least one sensor; generate a second screen related to the input data by using the input data on the basis of identifying that the input data corresponds to defined data; add the second screen to a list of screens to be displayed, in response to at least one swipe input received while the first screen is displayed; receive a swipe input while the first screen is displayed; and change a screen displayed through the display from the first screen to the second screen on the basis of the received swipe input after identifying that the input data corresponds to the defined data.

RESIN COMPOSITION FOR 3D PRINTING, METHOD FOR PREPARING SAME, AND TRANSPARENT ALIGNER COMPRISING SAME

Resumen de: WO2026146775A1

The present invention relates to a 3D printing resin composition for a transparent aligner, a method for preparing same, and a transparent aligner formed by 3D printing using same, the composition comprising 5-20 wt% UDMA (urethane dimethacrylate), 40-70 wt% BIS-GMA (bisphenol A-glycidyl methacrylate), 8-30 wt% BIS-EMA (ethoxylated bisphenol A dimethacrylate), 2-5 wt% TEGDMA (triethylene glycol dimethacrylate), 8-9 wt% modified PVA powder, 5-9 wt% of a filler, 0.72-3.7 wt% of a curing agent, and 0.1-1.0 wt% of an additive, wherein the transparent aligner can be modified to have a structure optimized for the oral cavities of individual users, and thus can maximize the aligning effect.

SYSTEMS AND METHODS FOR FRUCTOSAMINE SENSING

Resumen de: WO2026147606A1

A device for measurement of a concentration of glycated serum protein is disclosed, the device comprising: an analyte sensing portion configured to generate a signal associated with a concentration of a glycated serum protein, the analyte sensing portion comprising a flavin adenine dinucleotide (FAD)-dependent enzyme or an adenosine triphosphate (ATP)- dependent enzyme; a working electrode (WE); and a counter electrode (CE) and/or a reference electrode (RE). Methods of monitoring kidney disease in a subject using the device are also disclosed.

SYSTEMS AND METHODS FOR USING CONTINUOUS KETONE MONITORING TO PROVIDE FITNESS OPTIMIZATION AND DISEASE DIAGNOSIS

Resumen de: WO2026147609A1

Certain aspects of the present disclosure provide a therapy management system configured to monitor analyte levels of a host during a time period using one or more analyte sensors to obtain analyte data, the analyte levels comprising at least glucose levels and ketone levels, and determine a metabolic fitness of the host based, at least in part, on the analyte data. The therapy management system is further configured to provide therapy management guidance to the host based, at least in part, on the determined metabolic fitness to improve the metabolic fitness of the host. The therapy management guidance includes at least one of a diet or meal recommendation for the host, an exercise recommendation for the host, or a lifestyle recommendation for the host.

METHODS AND SYSTEMS USING MACHINE LEARNING TO PROVIDE RISK OF A CHRONIC DISEASE OR CONDITION

Resumen de: WO2026148109A1

A device may receive physical activity data for a subject, wherein the physical activity data comprises raw acceleration data. A device may derive a plurality of metrics from the raw acceleration data, wherein the plurality of metrics comprise a plurality of pattern-related metrics. A device may input the plurality of metrics into a deployed machine learning model. A device may be configured to perform receiving, from the deployed machine learning model, a physical activity score. A device may calculate a risk score for at least one disease or condition based on the physical activity score.

SYSTEMS AND METHODS FOR TRAINING MACHINE LEARNING MODELS FOR USE IN A PLURALITY OF SENSORY MONITORING DEVICES

Resumen de: US20260191463A1

0000 Methods and systems for receiving, by at least one processor, for each of a plurality of subjects at defined time intervals during a medical procedure, a subject-specific sensory metric output and a subject-specific sensor dataset. The subject-specific sensory metric output is outputted by a first sensory-monitoring device (SMD) of a first SMD type. The subject-specific sensor dataset is outputted by sensors monitoring a body of each subject from the plurality of subjects, and to be utilized by a second SMD of a second SMD type. The at least one processor executes code to correct for data collection deficiencies, to generate a training dataset for training a machine learning model (MLM) based on the subject-specific sensory metric output and a corrected subject-specific sensor dataset, to train the MLM, and to provide the trained MLM to the second SMD to facilitate medical actions during subsequent medical procedures.

MEDICAMENT DELIVERY SYSTEM USING LACTATE DATA

Nº publicación: WO2026147654A1 09/07/2026

Solicitante:

DEXCOM INC [US]
DEXCOM, INC.

Resumen de: WO2026147654A1

A method of delivering a medicament to a subject for the treatment of diabetes includes: receiving glucose data and lactate data for the subject; adjusting medicament therapy to be delivered to the subject based at least in part on the glucose data and the lactate data; and delivering the adjusted medicament therapy to the subject.