Alerta

GPC3-SPECIFIC ANTIBODIES, BINDING DOMAINS, AND RELATED PROTEINS AND USES THEREOF

Resumen de: US20260191905A1

0000 Described herein are anti-Glypican 3 (GPC3) antibodies and binding proteins including such binding domains, as well as nucleic acids encoding the same. The disclosure also features methods of using such antibodies, antigen-binding fragments, binding proteins, and nucleic acid to treat various diseases, such as cancer (e.g., HCC).

INDOLE PHTHALOCYANINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN TUMOR DIAGNOSIS IMAGING

Resumen de: US20260191998A1

The present invention relates to an indole phthalocyanine compound, a preparation method therefor, and a use thereof in tumor diagnosis imaging. Specifically, the present invention relates to a compound having a structure represented by general formula (I) or a pharmaceutically acceptable salt thereof, and a use thereof as a contrast agent. By using the contrast agent of the present invention, near-infrared real-time imaging having high contrast and a clear and distinguishable imaging result can be implemented.

Method and System for Determining Nanotube and/or Nanowire Lengths

Resumen de: US20260194437A1

0000 Methods of determining the length of nanowires and/or carbon nanotubes (CNTs), as well as systems for performing the same are provided. The methods and systems include the use of passing a polarized light beam through a sample container that is situated between parallel plate electrodes and subjected to a varying electric field. Measurement of the dichroism amplitude in the sample allows for the determination of nanowire and/or CNT lengths in the sample.

METHODS OF LIPID NANOPARTICLE MANUFACTURE AND COMPOSITIONS DERIVED THEREFROM

Resumen de: US20260191796A1

0000 Disclosed herein are methods of increasing the potency of nucleic acid loaded lipid nanoparticles (naLNPs) through certain novel and surprisingly superior LNP manufacturing techniques. Also disclosed are pharmaceutical compositions containing naLNPs manufactured according to the manufacturing methods described herein. The methods disclosed herein overcome major technical difficulties and high costs associated with previous LNP manufacturing techniques. The methods disclosed herein, therefore, greatly improve the industrial production of LNPs in unexpected ways thereby providing more potent naLNPs for nucleic acid delivery. Specifically, the invention disclosed herein are methods that show increased potency naLNPs due to increased mixing concentration of the lipids and mRNA during assembly.

SELECTIVE LASER HEATING OF CARBON NANOTUBES IN THE PRESENCE OF CARBON-BASED PRECURSORS

Resumen de: WO2026147948A1

Selective laser heating of carbon nanotubes in the presence of carbon-based precursors. The method involves supplying carbon nanotubes, supplying a carbon-based precursor composed of up to 15 carbon atoms along with hydrogen atoms, forming a mixture of the carbon nanotubes with the carbon-based precursor and applying selective laser heating to the mixture and graphitizing the carbon-based precursor.

METHOD FOR MANUFACTURING OXIDIZED MXENE AND CHEMIMEMRISTOR DEVICE USING THE SAME

Resumen de: EP4772869A1

A method for manufacturing oxidized MXene according to a preferred embodiment of the present disclosure may remove fluorine groups (F) on a surface of MXene and form OH functional groups through an oxidation process to effectively adsorb CO₂ molecules and reversibly change electrical conductance according to gas concentration. In addition, a chemimemristor device based on the oxidized MXene (M_n+1X_n(OH)₂) may simultaneously implement memristor and gas sensor functions in a single device, and maintain multiple levels of conductance depending on the concentration of adsorbed molecules, and implement, based thereon, reversible changes in conductance according to a concentration of CO₂ and multi-level information processing through its characteristics of learning multi-level operations and molecular adsorption history to mimic the human sense of smell and synaptic plasticity of the brain.

DISPOSITIVO REACTOR TRIBOELECTRICO CON DESCARGA DE MICROPLASMA, PROCEDIMIENTO DE PRODUCCION HIDROGENO Y AGUA ACTIVADA Y USO DEL AGUA ACTIVADA

非金属管用ガスセンサ及びその製造方法とガスモニタリング方法

Resumen de: CN119936130A

The invention provides a gas sensor for a non-metal pipe and a gas monitoring method. The gas sensor comprises MXene-based gel fibers and is prepared through the following steps that dispersion liquid containing MXene nanosheets serves as spinning liquid, the spinning liquid is injected into a spinning guide pipe, a sleeve is arranged on the outer wall of the spinning guide pipe, and the temperature of the sleeve is gradually reduced in the flowing direction of the spinning liquid; injecting the spinning solution into a coagulating bath through a spinning guide pipe; and collecting the fiber formed in the coagulating bath, and at least performing swelling, liquid nitrogen freezing and freeze drying to obtain the MXene-based gel fiber. According to the gas monitoring method, the gas sensor is used for monitoring environment gas and/or permeable gas of the non-metal pipe. The gas sensor provided by the invention is high in sensitivity, can detect low-concentration gas, and is suitable for monitoring gas permeation of a non-metal pipe.

PRECURSOR AND PREPARATION METHOD THEREFOR, POSITIVE ELECTRODE ACTIVE MATERIAL AND PREPARATION METHOD THEREFOR, POSITIVE ELECTRODE AND LITHIUM-ION BATTERY

Resumen de: EP4772475A1

The present disclosure provides a precursor of a positive electrode active material. A particle of the precursor includes a core and a shell covering the core. Each of the core and the shell is made of nickel cobalt manganese oxide or nickel cobalt manganese hydroxide. The core is doped with a fluxing agent, and the fluxing agent is selected from one or more of an oxide, a carbonic acid compound, and a hydroxide of a first metal element, and the first metal element at least is one of Sr, Li, Mg, Ni, Co, and Zr. The shell is doped with a reaction inhibitor. The reaction inhibitor is selected from one or more of lithium compounds, an oxide, a carbonic acid compound, a hydroxide, and other compounds of a second metal element, and the second metal element at least is one of Ta, W, Al, Mn, Mo, and La. A fluxing agent is disposed in the core of the particle of the precursor, and the reaction inhibitor is disposed in the shell, so that subsequent crystallization of the precursor develops from inside to outside. The present disclosure further provides a positive electrode active material and a preparation method therefor, a positive electrode comprising the positive electrode active material, a lithium-ion battery, and a preparation method for the precursor.

LITHIUM-SUPPLEMENTING ADDITIVE AND PREPARATION METHOD THEREFOR, POSITIVE ELECTRODE MATERIAL, POSITIVE ELECTRODE SHEET, AND BATTERY

Resumen de: EP4773237A1

The present application relates to the field of lithium battery technologies, and in particular, to a lithium-supplementing additive, and a method for preparing the same, a positive electrode material, a positive electrode plate, and a battery. The lithium-supplementing additive includes a lithium-containing compound, and the lithium-containing compound is selected from the group consisting of compounds represented by the following chemical formula (I): aLiFe_αMn_βM_1-α-βO_2-γX_γ·(1-a)Li₂Fe_δMn_εN_1-δ-εO_3-ηX_η, where M and N are each independently selected from a group consisting of Zr, Co, Sr, Al, Ni, W, Ti, Cu, Mg, Zn, Ca, Ba, Sc, Ga, Y, La, In, Ce, Ge, Hf, Sn, Nb, Ta, V, and Sb, and X is fluorine (F); 0.4 ≤ a ≤ 0.9, 0 < α ≤ 1, 0 ≤ β ≤ 1, 0 < (α+β) ≤ 1, 0 ≤ γ ≤ 0.1, 0 < δ ≤ 1, 0 ≤ ε ≤ 1, 0 < (δ+ε) ≤ 1, and 0 ≤ η ≤ 0.1. The lithium-supplementing additive provided in the present application can achieve stable and uniform lithium supplementation and enhance cycling stability.

PROCESSES FOR FORMING MULTIMETALLIC ALLOYS AND CARBON-SUPPORTED MULTIMETALLIC ALLOYS

Resumen de: US2025075298A1

Aspects of the present disclosure generally relate to processes for forming multimetallic alloys and carbon-supported multimetallic alloys. In an aspect, a process for forming carbon-supported PtNiCoRu nanoparticles is provided. The process includes forming a mixture comprising a platinum (Pt) metal source, a nickel (Ni) metal source, a cobalt (Co) metal source, a ruthenium (Ru) metal source, a carbon source, and a solvent. The process further includes heating the mixture at a temperature that is from about 80° C. to about 250° C. to form carbon-supported nanoparticles, the carbon-supported nanoparticles including a carbon support, and PtNiCoRu single phase alloy nanoparticles chemically bonded to the carbon support. Processes for forming carbon-supported PtNiCoRuFe nanoparticles are also provided. Processes for forming PtNiCoRu and PtNiCoRuFe alloy nanoparticles are also provided.

一种流化床元素掺杂硅碳负极材料及其制备方法、锂电池

Resumen de: CN122348189A

本发明涉及锂电池电极材料技术领域，具体涉及一种流化床元素掺杂硅碳负极材料及其制备方法、锂电池；制备方法包括：将硼锂化合物置于加热容器内，通入惰性载气，加热使其呈气态形式，载气连接流化床反应器气路，气态的硼锂化合物通入已提前投入多孔碳的流化床内，进行硼锂元素共掺杂；然后再通入硅烷混合气，气相裂解沉积硅，形成硼锂元素共掺杂硅碳材料，或者硅烷混合气的加入时机与气态硼锂化合物的加入时机相同；最后通入碳源，进行CVD碳包覆；本发明制备得到的碳包覆硼锂元素共掺杂硅碳材料能够提高离子扩散速率和电子电导率，显著提升电池动力学和首效。

量子メモリユニットおよび量子レジスタ

Resumen de: WO2024245528A1

The invention relates to a coherent single photon source (100) comprising: a nanodiamond (120) having a quantum emitter (140), wherein the nanodiamond (120) and the quantum emitter (140) are designed and configured such that the quantum emitter (140) emits coherent, indistinguishable photons (160). The invention further relates to a system (300) comprising: a first coherent single photon source (101); and a second coherent single photon source (102); wherein the first coherent single photon source (101) and the second coherent single photon source (102) are designed and configured such that photons (160) emitted from a first quantum emitter (151) of a first nanodiamond (121) of the first coherent single photon source (101) are indistinguishable from photons (160) emitted from a second quantum emitter (152) of a second nanodiamond (122) of the second coherent single photon source (102).

一种槐米碳点及其制备方法和应用

Resumen de: CN122343969A

本发明涉及一种槐米碳点及其制备方法和应用，所述槐米碳点的制备方法为将槐米粉碎、过筛后与乙二胺、纯化水混匀，超声处理后获得混合物，将该混合物进行加热处理，反应结束后冷却至室温，再经离心、过滤、透析以及冷冻干燥后得到槐米碳点。本发明通过传统中药材槐米作为碳源，采用一步水热法工艺制备槐米碳点，具有易于合成、良好水溶性、较高生物安全性等特点，与槐米水提液相比，槐米碳点具有显著的抗菌特性，对大肠杆菌、金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌的抗菌效果佳，尤其是对耐甲氧西林金黄色葡萄球菌的抗菌效果，且本发明制备获得的槐米碳点还具有抗氧化性以及可改善溃疡性结肠炎的功能。

一种多模式等离子体合成复相陶瓷纳米粉体的系统及方法

Resumen de: CN122343030A

本申请涉及先进陶瓷材料制备技术领域，具体公开了一种多模式等离子体合成复相陶瓷纳米粉体的系统及方法，该系统包括：等离子体反应单元，其设有阴极头、阳极头以及若干螺旋微进气口；气固分离单元；淬冷与收集单元。所述方法通过螺旋微进气口将硅源、氮气、钛源等原料以气固两相流形式送入反应单元，在阴极头和阳极头产生的高温等离子体射流中充分混合、反应，产物经气固分离、急速淬冷和后处理，得到碳化硅、氮化硅、氮化钛或其复相纳米粉体。该系统结构紧凑，通过独特的螺旋进气方式与等离子体射流耦合，实现了反应物的高度均匀分散与高效合成，尤其适用于制备高纯度、高性能的含钛复相陶瓷粉体。

一种铜掺杂硫化铋催化剂的制备方法与应用

Resumen de: CN122344744A

一种铜掺杂硫化铋催化剂的制备方法与应用，属于电化学催化领域。该制备方法包括：第一步将铋盐和铜盐溶于甲醇和N,N‑二甲基甲酰胺混合溶液作为前驱体A，将3‑巯基‑1丙烷磺酸钠（MPS）溶于甲醇和N,N‑二甲基甲酰胺混合溶液作为前驱体B。第二步使用高压活塞泵将前驱体A和B分别泵入预混器，经预热管道预热后进入微通道反应器并反应。第三步为收集催化剂清洗、干燥。该催化剂表面具有多孔纳米褶皱，内部为中空结构，相比一般催化剂有更大的比表面积和电化学活性面积，暴露更多的活性位点，使催化活性得到提高。该催化剂可应用于电催化还原二氧化碳生成甲酸，制备操作简单、成本低，具有工业放大可行性和很高的实用价值及推广价值。

一种MOF衍生碳限域CoNiFe三元金属SiC纳米线增强碳泡沫多功能复合材料、制备方法及其应用

Resumen de: CN122343093A

0001 本发明涉及多功能复合材料技术领域，具体涉及一种MOF衍生碳限域CoNiFe三元金属SiC纳米线增强碳泡沫多功能复合材料、制备方法及其应用，包括三维多孔碳泡沫支撑骨架、原位化学键合生长于骨架表面的SiC纳米线三维互穿网络、以及碳层完全包覆限域的CoNiFe三元金属纳米颗粒；配套制备方法涵盖梯度热解制碳泡沫、CVD原位生长SiC纳米线、羟基化活化、溶剂热负载MOF前驱体、可控热解限域核心步骤。本发明制得的材料兼具轻质高强、高活性、长循环稳定性与耐高温抗氧化性，可广泛应用于电催化、宽频吸波、热管理、多相催化载体等领域。

一种甘露糖修饰的纳米银簇、制备方法及其作为探针的应用

Resumen de: CN122344247A

本发明属于医药技术领域，公开了一种甘露糖修饰的纳米银簇、制备方法及其作为探针的应用，甘露糖修饰的纳米银簇由牛血清白蛋白‑纳米银簇和修饰的甘露糖通过酸胺缩合反应偶联所得，每个牛血清白蛋白分子上偶联14个修饰的甘露糖分子，所述甘露糖修饰的纳米银簇可作为探针应用于生物识别与靶向标记中，为受体‑配体相互作用研究和药物递送监测提供了新型可视化工具，推动了糖探针在生物医学检测和诊疗中的应用发展。

B、P共掺杂NiFe基碱性电极材料及其制备和电解海水应用

Resumen de: CN122344745A

0001 B、P共掺杂NiFe基碱性电极材料及其制备和电解海水应用，其属于电化学能源储存材料的技术领域。该制备方法以六水合硝酸镍，七水合硫酸亚铁作为金属盐，溶于去离子水中；常温下将泡沫镍基底放入完全溶解的混合液，将浸泡得到的催化剂在烘箱，自然冷却至室温；将材料取出，在烧杯中用NaBH<4>和NaOH的混合溶液处理，再次放置于管式炉中煅烧，自然冷却至室温，最后通过管式炉在催化剂上合成磷化物最后得到催化剂。该方法操作简单，无需繁琐的溶剂热反应等处理，易于大规模制备。在标准三电极体系中，将制得的电催化剂作为阳极，在1 M KOH+天然海水电解体系中进行电催化反应；电催化剂具有优异的水分解活性和稳定性。

一种电解水催化剂及其制备方法和应用

Resumen de: CN122344748A

0001 本发明公开了一种电解水催化剂及其制备方法和应用，属于电解水催化剂制备技术领域，本发明以泡沫镍为导电骨架，以钴钼酸水合物为基底前驱体，经磷化处理形成含CoP的复合结构，再利用原子层沉积技术（ALD）在其表面沉积Fe<2>O<3>，进一步结合原位电化学活化处理，得到电解水催化剂。本发明通过构建CoP与Fe<2>O<3>协同作用的多级异质界面结构，并经原位电化学活化优化电子环境，显著提升了催化剂的本征活性和双功能催化性能，所得催化剂在碱性条件下具有优异的析氢、析氧活性及长期稳定性。

一种低温环境免预热高强船板及制造方法

Resumen de: CN122344689A

本发明属于金属材料技术领域，提供了一种低温环境免预热高强船板及制造方法，采用低碳、低锰的化学成分体系，降低钢板的碳当量以及连铸坯的偏析倾向，并添加V‑N、Ti等微合金元素细化晶粒，精准控制（Ti+V）/N；显微组织包括铁素体、回火索氏体、弥散分布的珠光体，铁素体55.0%~70.0%，回火索氏体20.0%~30.0%，珠光体9.0%~20.0%，析出相平均尺寸为40~60nm。应用本发明生产的船板钢屈服强度为400~470MPa，抗拉强度530~580MPa，断后延伸率≥28.0%，‑80℃冲击功≥270J，‑10℃焊接后钢板的抗拉强度560~580MPa，热影响区‑60℃冲击功≥170J。

一种高熵BaTiO3纳米颗粒及其制备方法

Resumen de: CN122344004A

本发明涉及纳米功能材料领域，公开了一种高熵BaTiO3纳米颗粒及其制备方法，高熵BaTiO3纳米颗粒的化学通式为(Ba1‑xAx)(Ti1‑yBy)O3，0.05≤x≤1，0.05≤y≤1；该技术方案对BaTiO3的A位和B位进行元素掺杂制备高熵结构BaTiO3纳米颗粒，制成的高熵结构BaTiO3纳米颗粒具有优异的SOD样、CAT样和GPx样催化活性，该技术方案通过控制A位和B位掺杂元素的含量，有效提高BaTiO3纳米颗粒的晶格畸变程度和表面活性位点数量，提高BaTiO3纳米颗粒的类酶催化活性。

一种尺寸均匀的铪基双钙钛矿纳米晶及其制备方法

Resumen de: CN122344773A

本发明涉及发光材料技术领域，具体为一种尺寸均匀的铪基双钙钛矿纳米晶及其制备方法，旨在解决现有Cs2HfCl6纳米晶因采用一锅法制备导致的尺寸分布不均、质量低下及量子产率低的技术问题。本发明提出一种热注入制备方法，包括：S1、获取铯前驱体CsX的溶液L1；S2、获取铪前驱体Hf(acac)4的溶液L2；S3、将预热后的L1与L2溶液在惰性气氛下与预热的混合溶剂结合，随后注入含氯溶液引发反应，经冰水浴冷却后得到目标纳米晶。本发明通过有效控制钙钛矿纳米晶的结晶速度，使产物组分均匀、尺寸均一，量子效率与稳定性显著提升，有助于在发光器件、辐射探测等领域的应用。

钌基金属/氧化物异质结构催化剂及其制备方法和应用

Resumen de: CN122344750A

0001 本发明涉及新能源领域，公开了一种钌基金属/氧化物异质结构催化剂及其制备方法和应用，催化剂包括结晶态的Ru和非结晶态的RuO2，RuO2中掺杂有金属元素Bi，基于Ru和RuO2的总量，Ru的量为60‑70wt.%，RuO2的量为30‑40wt.%，Bi的量为1‑5wt.%。本发明构建了一种具有结晶态的Ru和非结晶态的RuO2的异质结构的催化剂，且催化剂中具有较多的氧空位，优化了催化剂的电子分布，制得的催化剂在全pH条件下均具有优异的HER催化活性。

一种口腔清洁用仿生组装颗粒及其制备方法和口腔清洁组合物

Nº publicación: CN122342716A 07/07/2026

Solicitante:

中国医科大学附属口腔医院北京大学口腔医院辽宁顺风新材料科技有限公司

Resumen de: CN122342716A

0001 本发明提供一种口腔清洁用仿生组装颗粒及其制备方法和口腔清洁组合物。所述颗粒具备珍珠粉纳米颗粒被包覆于透明质酸钠中的复合结构，其整体呈现有机/无机复合的软体组装形态。其在作为口腔清洁或者护理用的摩擦剂使用时，在保留珍珠粉颗粒清洁效果的同时，降低对牙齿等组织的磨损，并具有良好的生物相容性，且具有口腔护理功能。