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ARTIFICIAL INTELLIGENCE AND PHYSICS-BASED MODELS FOR EVALUATING MAGNETIC RESONANCE IMAGING DATA OF BLADDERS

Resumen de: WO2026207060A1

Presented herein are systems and methods of classifying risk for bladder cancer. A computing system can receive a plurality of MRI images from an MRI scanner. The computing system can identify a first ROI and a second ROI. The computing system can determine a plurality of features based on the first ROI. The computing system can determine a plurality of metrics based on the second ROI. The computing system can generate a classification of the first subject based on the plurality of features and the plurality of metrics. The computing system can provide an output based on the classification.

URETHANE (METH)ACRYLAMIDE AND CURABLE COMPOSITION COMPRISING SAME

Resumen de: WO2026205518A1

Problem To provide a urethane (meth)acrylamide oligomer having moisture resistance, weather resistance, transparency, tight adhesiveness, and chemical resistance, exhibiting a high level of heat resistance and good filler dispersibility, and being applicable to a wide range of applications, and to provide a curable composition comprising the urethane (meth)acrylamide oligomer. Solution A urethane (meth)acrylamide oligomer having a specific structural unit (general formula (1)) containing a carbonate group was discovered. The oligomer is applicable both as a material for additive manufacturing requiring toughness and as a thermal interface material requiring flexibility and heat resistance.

RESIN COMPOSITION, PRINTING METHOD, DENTAL PRODUCT OBTAINABLE BY THE PRINTING METHOD AND METHOD OF TREATING THE DENTAL PRODUCT

Resumen de: WO2026201743A1

The present invention relates to a resin composition comprising at least one methacrylate compound having at least two methacryl functional groups, at least one thiol compound having at least two thiol functional groups and at least one methallyl compound having at least two methallyl functional groups. The present invention further relates to a printing method, a dental product obtainable by the printing method, and a method of treating a dental product.

RECONSTRUCTION OF A THREE-DIMENSIONAL IMAGE OF A PATIENT

Resumen de: US20260301275A1

A method for reconstruction of 3D image of a patient is disclosed. The method comprises obtaining a projection set comprising a plurality of 2D CBCT projections of a first volume of the patient, and obtaining a 3D image of a second volume of the patient, wherein the second volume of the patient at least partially overlaps with the first volume of the patient. The method further comprises using acquisition information relating to the obtained projection set to generate, from the 3D image, synthetic projections of the second volume of the patient, and extending the projections of the first volume of the patient from the obtained projection set with information from the synthetic projections of the second volume of the patient. The method further comprises using the extended projections to generate a 3D image of a third volume of the patient, the third volume comprising a combination of the first and second volumes.

TOILET BIOMETRIC DATA COLLECTION DEVICE

Resumen de: US20260303938A1

0000 A biometric data collection device for a toilet includes a first compartment, a second compartment, and a bridge. The first compartment includes a first circuit board. The second compartment includes a second circuit board. The bridge is coupled to the first compartment and the second compartment and is configured to be supported by a rim of the toilet so that the first compartment is inside of a bowl of the toilet and the second compartment is outside of the bowl of the toilet. The bridge is changeable in length to fit different widths of the rim.

METHOD FOR MANUFACTURING ORTHODONTIC DEVICE BY USING INSERTION PATH

Resumen de: US20260294588A1

The present invention relates to a program for designing an orthodontic appliance. The method comprises: displaying, on a screen, the insertion path for determining the insertion direction of the appliance (S01); designating a tooth targeted for the insertion path setting (S02); setting the insertion path for the designated tooth in an arbitrary direction (S03) ; displaying, on the screen, undercuts of each tooth caused by the set insertion path (S04) ; calculating and storing depth values of the undercuts for each tooth (S05); and calculating and storing the total sum of undercut volumes for each tooth according to the insertion path (S06).

3D SCANNER FOR MINIMIZING MOTION BLUR

Resumen de: US20260303972A1

An intraoral 3D scanner includes at least one projector unit including a light source configured for emitting light; and a pattern generating element configured for generating a pattern of light to be projected onto a surface of an object. The scanner further includes one or more camera units, operatively coupled to the projector unit, each camera unit including an image sensor for capturing one or more image frames, wherein the image sensor includes a two-dimensional array of pixels arranged in rows and columns and is configured for capturing a given image frame by sequentially exposing individual rows within the two-dimensional array of pixels, wherein each row is exposed for a predefined exposure time. The scanner is configured for sequentially switching the light source on and off at a predefined frequency, wherein the light source is turned on for a predefined duration during which all rows are exposed simultaneously.

BIOPRINTING OF HIERARCHICALLY BRANCHING MICROVASCULAR NETWORKS

Resumen de: US20260295931A1

0000 A challenge to the clinical viability of large-scale tissue engineering is being able to perfuse entire constructs with blood supply that persists long-term. To accomplish this, tissue engineering needs to replicate the hierarchically branching networks of microvasculature that distribute homogeneous blood supply from arteries to capillary beds in natural tissues. Chaotic Printing can be adapted to extruding wide sheets of hydrogel containing hierarchically branching layers of multiple cell types that are native to vascular tissue. An in vitro “prevascularization” period can allow these cells to form into hollow tubular structures that mimic native microvasculature and can be perfused with blood supply. These prevascularized sheets can then be implanted in a subject to integrate with native arteries and veins and perfuse injured tissue with new blood supply.

Generation Of Artificial Contrast-Enhanced Radiological Images

Resumen de: US20260301131A1

The present invention relates to the technical field of generating artificial contrast-enhanced radiological images.

GENERATING FUNCTIONAL BRAIN MAPPINGS AND ACCOMPANYING REFERENCE INFORMATION

Resumen de: US20260294324A1

0000 A method for mapping functionally related brain regions of a subject. The method includes receiving a structural brain image and a dataset of resting-state functional MRI (rs-fMRI) three-dimensional (3D) image frames of a brain of the subject includes 3D image frames of the subject's brain over time. A functional connectivity map identifying groupings of functionally connected voxels is overlaid on the structural brain image. Spontaneous brain activations associated with each voxel in a grouping of functionally connected voxels are time-correlated with spontaneous brain activations in one or more other voxels in the grouping of functionally connected voxels. A reference location map for a pre-defined resting state network is generated, including reference information output. The reference location map includes brain reference locations that are informative of the one or more resting-state networks to assist a user in identifying the resting state network of the functional connectivity map.

PATIENT INTERFACE AND CUSHION THEREOF

Resumen de: US20260295189A1

A patient interface comprising a plenum chamber, a seal-forming structure constructed and arranged to form a seal with a region of the patient's face surrounding an entrance to the patient's airways, and a vent to allow a continuous flow of gases exhaled by the patient from an interior of the plenum chamber to ambient. The seal-forming structure may comprise a cushion, the cushion being deformable and resilient and at least partially formed by a lattice structure.

APPARATUS FOR THREE-DIMENSIONAL SENSING

Resumen de: US20260298906A1

An apparatus for three-dimensional sensing is disclosed. The apparatus comprises an electrode housing, comprising: two or more walls capable of encompassing a 3D model, wherein at least two walls are detachably connected to each other, forming at a connected state an angle greater than 0 degrees, between surfaces of each of the two or more walls; and wherein each wall comprises an electrode array, extending out from the wall towards the 3D model, configured to sense electrical activity of the 3D model.

Dental Appliance for Treatment of Bruxism And Sleep Apnea

Resumen de: US20260294672A1

0000 A dental appliance is disclosed. The appliance may include an arcuate base shaped to extend along at least a portion of an upper dental arch of a patient and match with a custom fit at least certain maxillary teeth of the patient. The appliance may further include a tongue-retention feature. The tongue-retention feature may connect to the arcuate base and comprise a palatal portion and a sublingual portion. The sublingual portion may cooperate with the palatal portion to form a cavity shaped to receive an anterior portion of a tongue of the patient therewithin. The palatal portion may have an exterior surface custom-formed to match at least a portion of a hard palate of the patient.

NOVEL 3D PRINTING CONCEPT FOR PHARMACEUTICAL DOSAGE FORMS VIA SELECTIVE LASER SINTERING

Resumen de: US20260294742A1

The present invention relates to a process for producing a Pharmaceutical dosage form by powder bed fusion selective laser 3-dimensional printing, in particular selective laser sintering 3-dimensional printing (SLS), and a pharmaceutical dosage form manufactured by that process.

METHOD AND DEVICE FOR DESIGNING IMPLANT SURGICAL GUIDE FOR BONE REDUCTION

Resumen de: US20260294584A1

Disclosed are a method and a device for designing an implant surgical guide for bone reduction. The method and the device for designing an implant surgical guide for bone reduction, according to an embodiment, can quickly and accurately perform bone reduction by designing a virtual bone reduction guide shape including a guide rail, when bone reduction is required for dental implant surgery.

LOCAL MANUFACTURING OF A MEDICAL STENT BASED ON A COMPUTATIONAL MODELED OUTCOME PREDICTION

Resumen de: US20260294653A1

A method for additive manufacturing of a medical stent includes generating, by a processor (152) executing instructions, a model of anatomy of a subject; obtaining a computer (140)-aided design (CAD) model of a stent; simulating deployment of the stent in the anatomy of the subject; determining whether the model of the stent satisfies an optimization metric based on the simulating, and optimizing the model of the stent by repeating obtaining and the simulating until the model of the stent satisfies the optimization metric. The stent is manufactured by additive manufacturing in response to the model of the stent being optimized.

PHOTOCROSSLINKABLE RECOMBINANT BACTERIAL COLLAGEN-LIKE PROTEINS

Resumen de: US20260297142A1

0000 Recombinant bacterial collagen-like protein with an amino acid sequence that is at least ≥60% identical to the amino acid sequence of SEQ ID NO:1 characterized in that the amino acid sequence comprises a deletion of at least 38 amino acids at the N-terminus of the amino acid sequence of SEQ ID NO:1 and that the recombinant collagen-like protein is functionalized with ethylenic unsaturated groups.

SYSTEM AND METHOD FOR MODELING NEUROLOGICAL ACTIVITY

Resumen de: US20260294322A1

0000 A system for modeling neurological activity includes a computer having one or more processors, one or more computer-readable tangible storage devices, and program instructions stored on at least one of the one or more storage devices. The program instructions are configured to receive electroencephalogram (“EEG”) data generated by an EEG device coupled to a plurality of electrodes disposed on a brain, the EEG data comprising a plurality of waveforms representative of electrical activity detected by the plurality of electrodes over a period of time; generate a graphical brain model representative of the brain; to convert the EEG data into a graphical EEG model representative of electrical activity; integrate the EEG model with the brain model, thereby enabling visualization of and interaction with the EEG model within the context of the brain model; and communicate the integrated EEG and brain model to a display.

Health Safety and Status System, Service, and Platform, and Corresponding Methods

Resumen de: US20260301894A1

0000 A computer-implemented method includes accessing, by a processor of health safety credential platform, an access requirement associated with a venue or service; accessing, a certified health status record associated with an individual; comparing the certified health status record to the access requirement; determining an access determination according to one or more access-evaluation parameters comprising a disease identifier, a test type, a sample-collection time, a test-result time, a time to live value, a vaccination date, an effective date range, a geographic rule, and a validity period; generating a machine-readable access object representing the access determination; and encoding, the machine-readable access object to suppress health-status information utilized in generating the access determination while preserving information indicating the access determination.

SYSTEM AND METHOD FOR ACCURATE ELECTRODE SITE MEASUREMENT ON BODY SURFACES, INCLUDING SITES NOT VISIBLE TO LIDAR, USING CALIBRATED TACTILE PROBES AND MOTION COMPENSATION

Resumen de: WO2026199041A1

The present invention relates to a system and method for automated electrode or sensor site mapping and placement guidance on a subject's body surface, including regions obscured by hair, fur, or subject positioning. The system combines LiDAR- based three-dimensional scanning with calibrated tactile probes to generate an accurate model of the body surface. An external reference landmark system comprising three or more fixed fiducial markers provides a static coordinate reference frame to compensate for subject movement during scanning and placement guidance. A processing unit integrates LiDAR and probe data, calculates electrode or sensor site locations based on standard or custom placement systems, and provides guidance for site placement through visual, auditory, or haptic feedback. The system is applicable to clinical and research applications, including electroencephalography (EEG), neuromodulation, and animal studies, where accurate and reproducible electrode or sensor placement is essential. The system reduces operator dependency, compensates for motion, and improves placement accuracy and efficiency.

KINEMATIC RECOMMENDATION ACROSS DEVICES USING MACHINE LEARNING

Resumen de: WO2026206497A1

A system preparing kinematic recommendations for athletes using artificial intelligence is disclosed. The system is programmed to sense personal physical data regarding a subject athlete, and optionally review environmental data, and historical performance and physical data related to the subject athlete. The system produces performance recommendations for that subject athlete, determines a best medium for providing the performance recommendations to the subject athlete based on their personal physical data, and provides the performance recommendations to the subject athlete via that determined best medium. The best medium can include an augmented reality interface worn by the athlete. The performance recommendations can be prepared by machine learning or artificial intelligence models designed to analyze athletic performances, and to communicate conversationally with the athlete.

DENTAL ZIRCONIA 3D-PRINTED ARTICLE HAVING COLOR AND TRANSLUCENCY GRADIENTS AND MANUFACTURING METHOD THEREFOR

Resumen de: WO2026205957A1

The present invention relates to a dental zirconia 3D-printed article having color and translucency gradients and a manufacturing method therefor and, specifically, to a dental zirconia 3D-printed article and a manufacturing method therefor, the dental zirconia 3D-printed article comprising at least two types of yttria-stabilized zirconia (YSZ) doped with different contents of yttria (Y2O3), wherein the at least two types of yttria-stabilized zirconia are selectively doped with a colorant to have gradients in color and translucency.

DENTAL PRODUCT FORMED BY 3D PRINTING AND METHOD FOR MANUFACTURING DENTAL PRODUCT

Resumen de: WO2026200932A1

The present application relates to a dental product formed by 3D printing, comprising: a first body, comprising a portion made of a first material; and a second body, connected to the first body and comprising a portion made of a second material, wherein the first material and the second material have different colors or transparencies. The dental product provided in the present application meets at least one application requirement.

SYSTEM FOR CUSTOM IMPLANT DESIGN AND INSTRUMENTATION

Resumen de: US20260294637A1

Systems and methods include a component of a bone implant that includes a patient specific bone contacting surface and, optionally, at least one protrusion adjacent to or extending from the patient specific bone contacting surface. The at least one protrusion is configured for engaging a bone preparation in the bone. To prepare the bone for receiving the component, one or more cutting tool templates may be used. The one or more cutting tool templates may be fabricated to have a patient specific bone contacting surface that engages the bone that is to receive the implant component. A cutting tool is engaged in one or more of one or more slots defined by the cutting tool template(s) to remove surface portions of the bone to create the bone preparation for engaging the protrusion. The patient specific bone contacting surface of the component engages the bone.

METHODS AND SYSTEMS FOR ASSISTING A DENTAL RESTORATION PROGRAMME

Nº publicación: WO2026201517A1 01/10/2026

Solicitante:

STRAUMANN INST AG [CH]
INSTITUT STRAUMANN AG

Resumen de: WO2026201517A1

Provided herein is a method (100) for preparing a prosthetic crown for a subject or assisting a dental restoration programme comprising one or more dental sessions for fitting a prosthetic crown into a subject, the method comprising: receiving a planning dataset, 3D- PLAN (120), wherein the 3D-PLAN comprises three-dimensional dental measurement data of the subject as presented prior to an intervention, wherein: the intervention includes implanting an implant in a defined pose for later addition of the prosthetic crown; and the 3D-PLAN: is used for a planning and execution of the intervention; and is used for a preparation of a preliminary design of the prosthetic crown; receiving a local 3D post- intervention measurement dataset, L3D-POI (140), wherein the L3D-POI has been obtained by a three-dimensional contactless measurement of the intervention site, wherein the intervention site comprises the implant, wherein the implant has been fitted to a jawbone of the subject to support the prosthetic crown, and the L3D-POI includes a three- dimensional measurement data of at least a coronal portion of the in situ implant; determining (200), from the 3D-PLAN (120) and L3D-POI (140), a 3D patient specific dental component, 3D PSDC, dataset (220), from which the 3D PSDC is able to be prepared; and outputting (230) the 3D PSDC dataset (220) for transmission (290) to a device (300) for additive manufacturing, thereby allowing an additive manufacture of a 3D printed PSDC, wherein the 3D p