Alerta

INCREASING THE AVAILABILITY OF FERMENTABLE SUGARS IN FERMENTATIONS

Resumen de: US20260218248A1

0000 Described is a method for increasing the amounts of fermentable sugars in fermentation substrates by treatment with a combination of an enzyme having transglucosidase activity and an enzyme having glucoamylase activity to hydrolyze oligo and/or polysaccharides that are not conventionally hydrolyzed by glucoamylase alone during fermentation. The method is most effective using fermentation substrates containing low amounts of maltose and maltotriose.

METHODS FOR STABILIZING PRODUCTION OF ACETYL-COENZYME A DERIVED COMPOUNDS

Resumen de: US20260218205A1

The present disclosure relates to the use of a switch for the production of heterologous non-catabolic compounds in microbial host cells. In one aspect, provided herein are genetically modified microorganisms that produce non-catabolic compounds more stably when serially cultured under aerobic conditions followed by microaerobic conditions, and methods of producing non-catabolic compounds by culturing the genetically modified microbes under such culture conditions. In another aspect, provided herein are genetically modified microorganisms that produce non-catabolic compounds more stably when serially cultured in the presence of maltose followed by the reduction or absence of maltose, and methods of producing non-catabolic compounds by culturing the genetically modified microbes under such culture conditions.

NOVEL NKR VARIANTS FOR INCREASED PRODUCTION OF ISOBUTANOL

Resumen de: US20260218137A1

The present invention relates to recombinant microorganisms comprising at least one nucleic acid molecule encoding a ketol-acid reductoisomerase (KARI) or modified NADH-dependent variant thereof, wherein said KARI is at least about 60% identical to SEQ ID NO: 2. In various aspects of the invention, the recombinant microorganisms may comprise an isobutanol producing metabolic pathway and can be used in methods of making isobutanol.

ENZYME, STRAIN FOR PRODUCING SALIDROSIDE, AND PRODUCTION METHOD

Resumen de: US20260218264A1

0000 Provided is an application of glucosyltransferase U8GT3 and/or poppy-derived tyrosine decarboxylase or a mutant thereof in the yeast synthesis of salidroside; further provided is an application of poppy-derived tyrosine decarboxylase or a mutant thereof in the yeast synthesis of tyrosol. The amino acid sequences of the poppy-derived tyrosine decarboxylase and the mutant thereof are respectively shown in SEQ ID NOs: 7-8, and the nucleotide sequences of the coding genes are respectively shown in SEQ ID NOs: 1-2; the amino acid sequence of the glucosyltransferase U8GT3 is shown in SEQ ID NO: 10, and the nucleotide sequence of the coding gene is shown in SEQ ID NO: 4.

METHOD FOR TREATING GRAINS TO PRODUCE MATERIAL USEFUL FOR CHEMICALS AND BIOFUELS

Resumen de: US20260218247A1

0000 A method for treating grains having starch and non-starch carbohydrates, wherein the starch is present in an amount of at least 10 wt. % based on the dry weight of the grain. The grain is contacted with a solution containing at least one α-hydroxysulfonic acid; and to react under acid hydrolysis conditions to produce a product that is suitable for producing chemicals and/or fuel.

BUTANOL-GENERATING BACTERIUM TRANSFORMANT OF GENUS HYDROGENOPHILUS

Resumen de: EP4782532A1

0001 A transformant obtained by introducing, into a Hydrogenophilus bacterium, any one of the following genes (1) to (5) is capable of efficiently producing butanol utilizing only carbon dioxide as a carbon source. (1) A gene encoding an enzyme having butyraldehyde dehydrogenase activity and a gene encoding an enzyme having butanol dehydrogenase activity (2) A gene encoding a multifunctional enzyme having butyraldehyde dehydrogenase activity and butanol dehydrogenase activity (3) A gene encoding an enzyme having butyraldehyde dehydrogenase activity and a gene encoding a multifunctional enzyme having butyraldehyde dehydrogenase activity and butanol dehydrogenase activity (4) A gene encoding an enzyme having butanol dehydrogenase activity and a gene encoding a multifunctional enzyme having butyraldehyde dehydrogenase activity and butanol dehydrogenase activity (5) A gene encoding an enzyme having butyraldehyde dehydrogenase activity, a gene encoding an enzyme having butanol dehydrogenase activity, and a gene encoding a multifunctional enzyme having butyraldehyde dehydrogenase activity and butanol dehydrogenase activity

Mutated Lipase

Resumen de: US20260209729A1

0000 The present invention relates to a mutated lipase. The present invention further relates to a gene encoding the lipase, and a vector and a host cell comprising the gene. In addition, the present invention further relates to use of the lipase.

METHOD FOR PRODUCING ETHANOL FROM LIGNOCELLULOSIC RAW MATERIAL

Resumen de: US20260209806A1

The present invention provides a method for producing ethanol with an improved flow rate of permeation in membrane separation. More specifically, the present invention provides a method for producing ethanol from a lignocellulosic raw material, comprising a first step of performing saccharification and fermentation in a reaction system containing a lignocellulosic raw material, a saccharification enzyme, a yeast, and water, thereby producing ethanol; and a second step of treating, with a separation membrane, a first mixture containing the ethanol, water, the yeast, the saccharification enzyme, and a reaction residue of the lignocellulosic raw material, obtained in the first step, thereby obtaining a mixture containing the ethanol and water, and a second mixture containing the yeast, the saccharification enzyme, water, and the reaction residue of the lignocellulosic raw material; wherein the concentration of suspended solids in the first mixture is from 4 to 9.5% by mass.

PROCESS FOR REDUCING SYRUP VISCOSITY IN THE BACKEND OF A PROCESS FOR PRODUCING A FERMENTATION PRODUCT

Resumen de: US20260206794A1

The present invention relates to a process for reducing syrup viscosity at the backend of a process for producing a fermentation product (e.g., ethanol from corn), comprising adding an oxidoreductase after the fermenting step, before whole stillage is subject to separation, to decrease the quantity of particles in the thin stillage by increasing the size of 5 particles in the whole stillage, thereby reducing the viscosity of syrup produced by evaporating the thin stillage.

WOOD-DERIVED LIGNIN COMPOSITION

Resumen de: US20260209520A1

A wood-derived lignin composition is disclosed. The wood-derived lignin composition comprises: —acid-insoluble lignin in an amount of 80-90 weight-% based on the total dry matter content of the lignin composition, wherein the average molecular weight of the lignin is 5000-15000 Da; —carbohydrates in an amount of 1.5-15 weight-% based on the total dry matter content of the lignin composition; —nitrogen in an amount of 0.2-1.5 weight-% based on the total dry matter content of the lignin composition; and wherein weight ratio of oxygen to carbon is at least 0.5 Further is disclosed a method for producing the wood-derived lignin composition.

GENETICALLY ENGINEERED YEAST CELLS AND METHODS OF USE THEREOF

Resumen de: US20260209656A1

0000 Provided herein are genetically modified yeast cells that recombinantly expresses a gene encoding a mutant beta-lyase. Also provided are methods of producing fermented products and methods of producing ethanol.

METHODS FOR PRODUCING ISOBUTENE FROM 3-METHYLCROTONIC ACID

Resumen de: US20260209804A1

0000 Described are methods for the production of isobutene comprising the enzymatic conversion of 3-methylcrotonic acid into isobutene wherein said 3-methylcrotonic acid is obtained by the enzymatic conversion of 3-methylcrotonyl-CoA into 3-methylcrotonic acid or wherein said 3-methylcrotonic acid is obtained by the enzymatic conversion of 3-hydroxyisovalerate (HIV) into 3-methylcrotonic acid. It is described that the enzymatic conversion of 3-methylcrotonic acid into isobutene can, e.g., be achieved by making use of a 3-methylcrotonic acid decarboxylase, preferably an FMN-dependent decarboxylase associated with an FMN prenyl transferase, an aconitate decarboxylase (EC 4.1.1.6), a methylcrotonyl-CoA carboxylase (EC 6.4.1.4), or a geranoyl-CoA carboxylase (EC 6.4.1.5).

GENE EXPRESSION SYSTEM FOR PROBIOTIC MICROORGANISMS

Resumen de: US20260199408A1

0000 Provided herein are recombinant microorganisms that express a subject polypeptide. Microorganisms can comprise an expression construct comprising a flagellin promoter operatively linked with a heterologous nucleotide sequence encoding the subject polypeptide. The flagellin promoter sequence can comprise a genetic modification that reduces CsrA inhibition of translation. Microorganisms also can comprise a genetic modification that reduces FlgM inhibition of SigD initiation of transcription. The target polypeptide can be an aldehyde dehydrogenase. Such microorganisms are useful in the treatment of alcohol hangover.

SINTERED ORE MANUFACTURING METHOD

Resumen de: US20260201495A1

0000 Sintering materials include: a crushed product of a compression-molded product obtained by crushing the compression-molded product obtained by compressing and molding an aggregate of carbonized wood; and at least one of coke breeze or anthracite, and the compression-molded product has an envelope density of 0.6 g/cm<3 >or more.

SYSTEMS AND APPARATUS FOR PRODUCTION OF HIGH-CARBON BIOGENIC REAGENTS

Resumen de: US20260201264A1

0000 This invention provides processes and systems for converting biomass into high carbon biogenic reagents that are suitable for a variety of commercial applications. Some embodiments employ pyrolysis in the presence of an inert gas to generate hot pyrolyzed solids, condensable vapors, and non-condensable gases, followed by separation of vapors and gases, and cooling of the hot pyrolyzed solids in the presence of the inert gas. Additives may be introduced during processing or combined with the reagent, or both. The biogenic reagent may include at least 70 wt %, 80 wt %, 90 wt %, 95 wt %, or more total carbon on a dry basis. The biogenic reagent may have an energy content of at least 12,000 Btu/lb, 13,000 Btu/lb, 14,000 Btu/lb, or 14,500 Btu/lb on a dry basis. The biogenic reagent may be formed into fine powders, or structural objects.

COKE PRODUCTION METHOD

Resumen de: EP4775647A1

0001 Provided is a method of producing coke that does not require any operations posing a risk of ignition and that is capable of producing high-strength coke even when using biomass-derived raw materials. A method of producing coke by charging blended coal into a coke oven and carbonizing the blended coal includes preparing the blended coal by blending 1 mass% or more and 10 mass% or less of a carbonaceous material B, which is obtained by heat treating biomass having a ratio of particles with a particle size of 125 µm or less of 50 mass% or more, with a carbonaceous material A, which has a ratio of particles with a particle size of 3 mm or more of 10 mass% or more and 30 mass% or less, and a ratio of particles with a particle size of 0.5 mm or more of 60 mass% or more.

AUTONOMOUS DEVICE FOR IN-FIELD CONVERSION OF BIOMASS INTO BIOCHAR

Resumen de: US20260193148A1

Systems, methods and apparatus for the thermal conversion of biomass into biochar. A mobile platform may be used to maneuver a mobile biochar generation system within a field of biomass. The biomass may be harvested, preprocessed and pyrolyzed. After pyrolyzation, the biochar may be cooled to a predetermined temperature by integrating water and liquid nutrients into the biochar. The system may then control the application of the infused biochar by adjusting a spreading attachment and a plowing attachment.

SYSTEM AND METHOD FOR DUAL BIOFUEL PRODUCTION FROM LIGNOCELLULOSIC BIOMASS

Resumen de: WO2026143290A1

A process that enables simultaneous conversion of lignocellulosic biomass into a solution of fermentable sugars and combustible pellets is disclosed. The process integrates the biomass fractionation step with the hydrolysis of polysaccharides, resulting in a solid with high calorific value and ethanol production from polysaccharides. The process involves liquefaction of the lignocellulosic biomass with acid and then diluting the acid-treated lignocellulosic biomass with water and hydrolyzing the polysaccharides present in the lignocellulosic biomass, thereby producing a sugar solution. The process also includes separating the acid from the sugar solution; neutralizing the sugar solution using alkaline reagents; washing the solid fraction to remove residual acid; and drying and pelletizing to form combustible pellets. The process is suitable for use with a wide range of biomass sources, including forest wood residues, bark, agricultural waste, construction refuse, and recycled cardboard.

PYROLYZER SYSTEMS AND METHODS

Resumen de: US20260193539A1

0000 Embodiments include a system having a pyrolyzer cell. The pyrolyzer cell may include a jacketed wall. The jacketed wall may include a first jacket. The first jacket may include a first inner wall, a first outer wall, and a first fluted medium between the first inner wall and the first outer wall. The first fluted medium forms a first plurality of channels, and each channel may be defined by alternating ridges and valleys formed in the first fluted medium. The system also may include a second jacket. The second jacket may include a second inner wall, a second outer wall, and a second fluted medium between the second inner wall and the second outer wall. The second fluted medium may form a second plurality of channels, and each channel may be defined by alternating ridges and valleys formed in the second fluted medium. Methods are also described.

NISIN FOR ETHANOL MICROBIAL CONTROL AND CLEANING

Resumen de: WO2026147750A1

Compositions, methods, and systems for controlling microbial populations within an ethanol production system. Nisin and other components may be applied to various parts of an ethanol production system, such as of a mash cooler, a mash tank, a fermentation tank, a fermentation cooler, a drain, a yeast propagation tank, a liquefaction tank, a slurry tank, a strainer, a jet cooker, a hammer mill, a beerwell, a backset, a heat exchanger, a urea tank, a premix tank, or combinations thereof.

AMMONIA TREATMENT OF DENSIFIABLE CELLULOSIC BIOMASS FEEDSTOCK

Resumen de: US20260193421A1

In one example, a method of plasticizing at least a portion of lignin within a lignocellulosic biomass by mixing the biomass with anhydrous ammonia at a sub-ambient temperature and continuously conveying the mixture of lignocellulosic biomass and anhydrous ammonia through a reactor. At least a portion of the anhydrous ammonia is removed from the mixture. The lignocellulosic biomass having plasticized lignin is molded into a repeated shape.

α-AMYLASE MUTANT, PREPARATION METHOD THEREFOR, AND USE THEREOF

Resumen de: WO2026145743A1

Provided are an α-amylase mutant having improved thermal stability and/or low pH stability, a polynucleotide encoding the α-amylase mutant, a recombinant expression vector comprising the polynucleotide, a host cell expressing the α-amylase mutant, a composition comprising the α-amylase mutant, a preparation method therefor, and a use thereof.

IMMOBILISED LIPASE AND METHOD OF PRODUCING BIODIESEL USING THE SAME

Resumen de: US20260193627A1

The invention relates to a lipase isolated from the goat gut rumen metagenome having protein SEQ ID 1 of 298 amino acids and being encoded for by gene SEQ ID1. The invention relates more specifically to this lipase being engineered to be an immobilised lipase, the same being immobilised on Polyethylene glycol (PEG) coated iron Magnetic Nanoparticles (MNPs). The immobilised lipase is indicated for use in a method of converting a waste oil to biodiesel, the method comprising utilizing the immobilised lipase to catalyse the conversion of said waste oils to biodiesel in the presence of a short-chain alcohol. The triacylglycerol in the waste oils being converted to alkyl esters (biodiesel) and glycerin in a reaction with an alcohol which is catalysed by said lipases.

CO-FERMENTATION OF MIXED BIOMASS FEEDSTOCKS USING THERMOPHILIC BACTERIAL CO-CULTURES

Resumen de: WO2025049898A2

A method for direct simultaneous co-fermentation of two or more insoluble biomass feedstocks using thermophilic bacterial co-cultures.

GENETICALLY MODIFIED YEAST FOR PRODUCTION OF NON-ALCOHOLIC BEVERAGES

Nº publicación: EP4771038A2 08/07/2026

Solicitante:

BERKELEY FERMENTATION SCIENCE INC [US]
Berkeley Fermentation Science Inc.

Resumen de: MX2026002459A

Provided herein are genetically modified yeast cells that comprise genetic modifications to reduce sensory detection of one or more wort-associated off-flavors of a fermented beverage and the cell is not capable of converting maltose and/or maltotriose to ethanol. Also provided are methods of producing fermented products (e.g., non-alcoholic fermented beverages) using the genetically modified yeast cells described herein.