Resumen de: US2025288624A1
Provided herein are compositions comprising Escherichia coli (E. coli), Saccharomyces boulardii (S. boulardii), Lactobacillus plantarum (L. plantarum), and/or Ensifer meliloti (E. meliloti) and a first stabilizing excipient. Also provided herein are methods of delivering E. coli, S. boulardii, L. plantarum, and/or E. meliloti to a subject in need thereof, methods of inducing bacterial growth in a subject or in a cell, tissue, or biological sample, and methods of inhibiting an enteric pathogen in a subject or in a cell, tissue, or biological sample. Further provided herein are methods of treating dysbiosis in a subject in need thereof.
Resumen de: US2025288620A1
A biocontrol agent of the present invention, comprising one or more of the selected, isolated bacteria disclosed herein, is useful in methods of protecting plants against disease or damage by plant pathogens. A method comprises applying a biocontrol agent to plants, plant seeds, or media or soil surrounding plants provide disease protection to plants or plants produced from the contacted plant seeds. Biocontrol agents of the present invention are useful in horticulture, aquaculture, aeroculture, hydroponic culture, agriculture and all types of plant growing conditions to protect plants from a variety of plant bacterial, fungal, and viral diseases. The compositions and methods of the present invention are effective against plant pathogens.
Resumen de: US2025287955A1
A method of controlling or preventing pathogenic damage and/or pest damage in a plant propagation material, a plant, part of a plant and/or plant organ, comprising applying on the plant, part of the plant, plant organ, plant propagation material or a surrounding area thereof a phytoprotective agent comprising an enzyme and an insecticide.
Resumen de: WO2024102921A1
The present invention relates to methods for stabilizing liquid bacterial endospores compositions. The present invention also relates to multi-functional osmotic preservation strategies for liquid Bacillus endospore suspensions.
Resumen de: JP2025134630A
【課題】経皮投与によっても効果が得られる、チョウ目昆虫におけるRNAi効率の向上剤、及びチョウ目昆虫の防除剤を提供すること。【解決手段】チョウ目昆虫における、目的遺伝子に対するRNAi効率の向上剤であり、所定の遺伝子の発現を抑制する二本鎖RNAと、ナノ粒子と、界面活性剤との複合体を含有し、上記所定の遺伝子が、チョウ目昆虫の目的遺伝子、二本鎖RNA分解酵素をコードする少なくとも2つの遺伝子、並びに、PINドメインを有する核酸分解酵素をコードする少なくとも1つの遺伝子、及び/又は、皮膚のキチン合成に関与する酵素をコードする少なくとも2つの遺伝子を含む、向上剤。【選択図】なし
Resumen de: AU2023376812A1
The present application relates to compounds and pharmaceutically acceptable salts thereof, compositions thereof, and their use in the reduction or prevention of transmission of a parasite or vector borne disease.
Nº publicación: EP4615979A1 17/09/2025
Solicitante:
MARTIN LUTHER UNIV HALLE WITTENBERG [DE]
Martin-Luther-Universit\u00E4t Halle-Wittenberg
Resumen de: WO2024100038A1
The invention relates to newly identified nucleic acids, ribonucleic acids (RNAs) and deoxyribonucleic acids (DNAs), specifically esiRNAs/ERNAs (effective small interfering RNAs) and RNAs derived therefrom, as well as eASO (effective antisense DNA oligonucleotides), collectively referred to as eNAs (effective nucleic acids), which are used in RNA silencing/RNAi or RNA silencing/antisense methods, as active agents against various variable plant pathogens. To identify the eNAs, a screening method, hereinafter also referred to as "eNA screen", was applied for the first time in standardised form to objective (target) RNAs of various plant pathogens. As a result, a new class of these active agents against these pathogens was identified and successfully used against them. The invention further relates to the construction of double-stranded ribonucleic acids, edsRNAs (effectively active double-stranded RNAs), which contain nucleotide sequences of identified esiRNAs/ERNAs or related RNAs derived therefrom, and which can be successfully used in the RNA silencing/RNAi methods as active agents in plant protection against these same variable plant pathogens*.